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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Academic Journal

Ye, T.; Zhong, Z.; Chen, Y.; Lauwers, H.; De Lombaerde, E.; Gontsarik, M.; Van Lysebetten, D.; De Geest, B.G.; Cappellesso, F.; Laoui, D.; Deswarte, K.; Lambrecht, B.N.; Lienenklaus, S.; Sanders, N.N.; De Koker, S.

In: Biomaterials. (Biomaterials, December 2024, 311)

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Lipid-Polyglutamate Nanoparticle Vaccine Platform

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Van Lysebetten, D.; Golba, B.; Ye, T.; Zhong, Z.; Kasmi, S.; Lamoot, A.; Chen, Y.; Van Herck, S.; De Geest, B.G.; Malfanti, A.; Vicent, M.J.; Deswarte, K.; Lambrecht, B.N.; Koynov, K.; Sanders, N.N.; Lienenklaus, S.; David, S.A.; De Koker, S.

In: ACS Applied Materials and Interfaces. (ACS Applied Materials and Interfaces, 10 February 2021, 13(5):6011-6022)

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NMR structure of µ-conotoxin GIIIC: Leucine 18 induces local repacking of the N-terminus resulting in reduced Nav channel potency

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Harvey, P.J.; Kurniawan, N.D.; Van Lysebetten, D.; Dash, T.S.; Hill, J.M.; Durek, T.; Craik, D.J.; Finol-Urdaneta, R.K.; McArthur, J.R.; Adams, D.J.

In: Molecules. (Molecules, 22 October 2018, 23(10))

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A Thiolactone Strategy for Straightforward Synthesis of Disulfide-Linked Side-Chain-to-Tail Cyclic Peptides Featuring an N-Terminal Modification Handle

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Van Lysebetten, D.; Felissati, S.; Antonatou, E.; Carrette, L.L.G.; Espeel, P.; Focquet, E.; Du Prez, F.E.; Madder, A.

In: ChemBioChem. (ChemBioChem, 16 March 2018, 19(6):641-646)

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Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities

Academic Journal

Parmar, A.; Iyer, A.; Singh, I.; Prior, S.H.; Van Lysebetten, D.; Madder, A.; Vincent, C.S.; Taylor, E.J.; Breukink, E.

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Efficient total syntheses and biological activities of two teixobactin analogues

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Parmar, A.; Iyer, A.; Singh, I.; Van Lysebetten, D.; Madder, A.; Vincent, C.S.; Taylor, E.J.; Prior, S.H.

In: Chemical Communications. (Chemical Communications, 2016, 52(36):6060-6063)

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Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates

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Ruiz García, Y.; Iyer, A.; Van Lysebetten, D.; Madder, A.; Vladimir Pabon, Y.; Edvard Smith, C.I.; Louage, B.; De Geest, B.G.; Honcharenko, M.; Strömberg, R.

In: Chemical Communications. (Chemical Communications, 12 October 2015, 51(99):17552-17555)

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Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake

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Iyer, A.; Van Lysebetten, D.; Ruiz García, Y.; Madder, A.; Louage, B.; De Geest, B.G.

In: Organic and Biomolecular Chemistry. (Organic and Biomolecular Chemistry, 7 April 2015, 13(13):3856-3862)

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CYCLISATION OF PEPTIDES VIA A THIOLACTONE STRATEGY

Academic Journal

Van Lysebetten, D.; Felissati, S.; Focquet, E.; Abdhouni, Y.; Espeel, P.; Carrette, L.; Du Prez, F. E.; Madder, A.

JOURNAL OF PEPTIDE SCIENCE; SEP 2016, 22 pS210-pS210, 1p. Supplement: S2

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