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Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities

Academic Journal

Cheff, DM; Muotri, AR; Stockwell, BR; Schmidt, EE; Ran, QT; Kartha, RV; Johnson, SC; Mittal, P; Arner, ESJ; Wigby, KM; Hall, MD; Ramesh, SK

Orphanet journal of rare diseases. 16(1):446

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Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

Academic Journal

Ran, QT; Liang, HY; Gu, MJ; Qi, WB; Walter, CA; Roberts, LJ; Herman, B; Richardson, A; Van Remmen, H

JOURNAL OF BIOLOGICAL CHEMISTRY; DEC 31 2004, 279 53, p55137-p55146, 10p.

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Embryonic fibroblasts from Gpx4(+/-) mice: A novel model for studying the role of membrane peroxidation in biological processes

Academic Journal

Ran, QT; Van Remmen, H; Gu, MJ; Qi, WB; Roberts, LJ; Prolla, T; Richardson, A

FREE RADICAL BIOLOGY AND MEDICINE; NOV 1 2003, 35 9, p1101-p1109, 9p.

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The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Academic Journal

Yant, LJ; Ran, QT; Rao, L; Van Remmen, H; Shibatani, T; Belter, JG; Motta, L; Richardson, A; Prolla, TA

FREE RADICAL BIOLOGY AND MEDICINE; FEB 15 2003, 34 4, p496-p502, 7p.

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Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells

Academic Journal

Ran, QT; Wadhwa, R; Bischof, O; Venable, S; Smith, JR; Pereira-Smith, OM

EXPERIMENTAL CELL RESEARCH; FEB 1 2001, 263 1, p156-p162, 7p.

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Identification of an alternatively spliced form of the Tat Interactive Protein (Tip60), Tip60(beta)

Academic Journal

Ran, QT; Pereira-Smith, OM

GENE; NOV 27 2000, 258 1-2, p141-p146, 6p.

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Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75

Academic Journal

Ran, QT; Wadhwa, R; Kawai, R; Kaul, SC; Sifers, RN; Bick, RJ; Smith, JR; Pereira-Smith, OM

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; AUG 18 2000, 275 1, p174-p179, 6p.

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Genetic approaches to the study of replicative senescence

Academic Journal

Ran, QT; Pereira-Smith, OM

EXPERIMENTAL GERONTOLOGY; FEB 2000, 35 1, p7-p13, 7p.

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MEFs (mouse embryonic fibroblasts) with decreased GPx4 (PHGPx) expression are more prone to oxidative stress.

Academic Journal

Ran, QT; VanRemmen, P; Prolla, T; Richardson, A

FREE RADICAL BIOLOGY AND MEDICINE; 2001, 31 pS96-pS96, 1p. Supplement: 1

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