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Peroxide-cleavable linkers for antibody-drug conjugates

Academic Journal

Ashman, N.; Bargh, J.D.; Walsh, S.J.; Spring, D.R.; Carroll, J.S.; Greenwood, R.D.; Tiberghien, A.

In: Chemical Communications. (Chemical Communications, 18 January 2023, 59(13):1841-1844)

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All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading

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Dannheim, F.M.; Walsh, S.J.; Orozco, C.T.; Hansen, A.H.; Bargh, J.D.; Jackson, S.E.; Spring, D.R.; Carroll, J.S.; Bond, N.J.; Parker, J.S.

In: Chemical Science. (Chemical Science, 20 July 2022, 13(30):8781-8790)

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Rapid and robust cysteine bioconjugation with vinylheteroarenes

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Seki, H.; Walsh, S.J.; Bargh, J.D.; Spring, D.R.; Carroll, J.; Parker, J.S.

In: Chemical Science. (Chemical Science, 14 July 2021, 12(26):9060-9068)

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A dual-enzyme cleavable linker for antibody-drug conjugates

Academic Journal

Bargh, J.D.; Walsh, S.J.; Ashman, N.; Spring, D.R.; Carroll, J.S.; Isidro-Llobet, A.

In: Chemical Communications. (Chemical Communications, 11 April 2021, 57(28):3457-3460)

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General dual functionalisation of biomacromoleculesviaa cysteine bridging strategy

Academic Journal

Walsh, S.J.; Iegre, J.; Seki, H.; Bargh, J.D.; Sore, H.F.; Spring, D.R.; Carroll, J.S.; Parker, J.S.

In: Organic and Biomolecular Chemistry. (Organic and Biomolecular Chemistry, 14 June 2020, 18(22):4224-4230)

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Sulfatase-cleavable linkers for antibody-drug conjugates

Academic Journal

Bargh, J.D.; Walsh, S.J.; Spring, D.R.; Omarjee, S.; Carroll, J.S.; Isidro-Llobet, A.

In: Chemical Science. (Chemical Science, 7 March 2020, 11(9):2375-2380)

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Non-internalising antibody-drug conjugates

Academic Journal

Ashman, N.; Spring, D.R.; Bargh, J.D.

In: Chemical Society Reviews. (Chemical Society Reviews, 2022, 13)

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Site-selective modification strategies in antibody-drug conjugates

Academic Journal

Walsh, S.J.; Bargh, J.D.; Dannheim, F.M.; Hanby, A.R.; Seki, H.; Counsell, A.J.; Ou, X.; Fowler, E.; Ashman, N.; Takada, Y.; Spring, D.R.; Carroll, J.S.; Isidro-Llobet, A.; Parker, J.S.

In: Chemical Society Reviews. (Chemical Society Reviews, 21 January 2021, 50(2):1305-1353)

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Cleavable linkers in antibody-drug conjugates

Academic Journal

Bargh, J.D.; Spring, D.R.; Isidro-Llobet, A.; Parker, J.S.

In: Chemical Society Reviews. (Chemical Society Reviews, 21 August 2019, 48(16):4361-4374)

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