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e-Article

Left atrial isomerism associated with asplenia: prenatal echocardiographic detection of complex congenital cardiac malformations.
Document Type
Academic Journal
Source
Journal of the American College of Cardiology (JACC) (J AM COLL CARDIOL), Nov1984; 4(5): 1015-1020. (6p)
Subject
Language
English
ISSN
0735-1097
Abstract
Complex congenital heart disease with suspected isomerism of the atria was diagnosed in two fetuses of 20 and 29 weeks' gestation using two-dimensional and M-mode scanning techniques. The first pregnancy was terminated at 21 weeks' gestation and stillbirth occurred at 31 weeks' gestation in the second pregnancy. At postmortem examination, a thoracoabdominal discordancy was found; the spleen was absent and the arrangement of the abdominal vessels was as anticipated for asplenia, but the thoracic situs revealed a bilateral right-sided arrangement with left isomerism of the atria. The heart, otherwise, showed complex abnormalities as anticipated for asplenia.