e-Article
CNS-associated macrophages shape the inflammatory response in a mouse model of Parkinson’s disease
Document Type
Brief Communication
Author
Source
Nature Communications. 14(1)
Subject
Language
English
ISSN
2041-1723
Abstract
In an alpha-synuclein (α-syn) model of Parkinson’s disease (PD), Schonhoff and colleagues have shown that central nervous system (CNS)-associated macrophages (CAMs), but not microglia, potentially orchestrate CD4+ T cell recruitment and mediate an α-syn-induced inflammatory makeup.