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e-Article

Improper Application of a Rivastigmine Patch to the Back of the Neck Induced Toxic Symptoms
Document Type
Journal Article
Source
Internal Medicine. 2023, 62(21):3247
Subject
Alzheimer's disease
addiction
cholinergic
pharmacokinetics
rivastigmine
toxicity
Language
English
ISSN
0918-2918
1349-7235
Abstract
Rivastigmine is a highly effective drug for treating Alzheimer's disease. However, its addiction can be fatal, so proper use of this transdermal drug is needed. We herein report an 85-year-old woman with Alzheimer's disease who inappropriately placed rivastigmine patches on the back of her neck. She suffered from acute cholinergic syndrome, hypersalivation, anorexia, dyspnea, and vomiting. These symptoms disappeared when the improper use of rivastigmine patches was ceased. This case serves as a warning to physicians and pharmacists of the risk associated with the improper placement of rivastigmine patches.