e-Article
Giant VEP after remission of childhood absence epilepsy in a case of Alice in Wonderland syndrome / 小児欠神てんかん寛解後に不思議の国のアリス症候群を発症しgiant VEPを認めた一例
Document Type
Journal Article
Author
Source
臨床神経生理学 / Japanese Journal of Clinical Neurophysiology. 2020, 48(3):121
Subject
Language
Japanese
ISSN
1345-7101
2188-031X
2188-031X
Abstract
We describe an abnormal visual evoked potential (VEP) after the remission of childhood absence epilepsy in a patient with Alice in Wonderland syndrome (AIWS). A 10-year-old girl presented with abnormal visual symptoms (micropsia and macropsia). Although the VEP latencies were normal, the VEP amplitude showed significant high amplitudes of both N75–P100 and P100–N145 on Oz–Fz. Moreover, SPECT showed low cerebral blood flow in the right parietal area. These results may have been caused by cortical hyperexcitability due to the patient’s history of epilepsy. The pathophysiology of AIWS may be easy to assess with simultaneous VEP and SPECT.