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e-Article

Mechanisms of Disease: erythropoietin-an old hormone with a new mission?
Document Type
Academic Journal
Source
Nature Clinical Practice Cardiovascular Medicine. Oct, 2006, Vol. 3 Issue 10, p563, 10 p.
Subject
Language
English
ISSN
1743-4297
Abstract
The major physiological function of erythropoietin is the induction of erythropoiesis. A growing body of evidence indicates, however, that this hormone has tissue-protective effects and prevents tissue damage during ischemia and inflammation. This review article summarizes the present knowledge on the cardiovascular and renal protective effects of erythropoietin and discusses the possible underlying mechanisms.[box 1]
Author(s): Danilo Fliser [1]; Ferdinand H Bahlmann [1]; Kirsten deGroot [2]; Hermann Haller (corresponding author) [1] Introduction Pleiotropic effects of established therapies have gained considerable interest in the medical community. [...]