e-Article
The contribution of tissue removal to lumen improvement after directional coronary atherectomy
Document Type
Periodical
Author
Source
American Journal of Cardiology. Oct 1, 1994, Vol. 74 Issue 7, p647, 4 p.
Subject
Language
ISSN
0002-9149
Abstract
The contribution of tissue removal to lumen improvement after directional coronary atherectomy remains controversial. The purpose of this study was to validate the intravascular ultrasound measurement of plaque volume and use it to study the contribution of tissue removal to lumen improvement after directional coronary atherectomy. With use of intravascular ultrasound, 12 human coronary vessels were imaged in vitro. With use of computer-assisted planimetry, the external elastic membrane and lumen cross-sectional areas were manually traced and the plaque + media area was calculated at 1 mm axial intervals. Then, plaque + media volume was calculated by Simpson's rule. After imaging, ultrasound measurement of plaque + media volume were compared with histologic measurements. Similarly, volumetric intravascular ultrasound imaging was performed before and after directional atherectomy in 47 patients. In vitro, the mean plaque + media volume measured by intravascular ultrasound was 134.0 [+ or -] 94.8 [mm.sup.3] and compared well with that derived by histology (187.4 [+ or -] 128.8 [mm.sup.3], r = 0.96, p