e-Article
A Comparison of Genicular Nerve Blockade With Corticosteroids Using Either Classical Anatomical Targets vs Revised Targets for Pain and Function in Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial
MUSCULOSKELETAL, REHABILITATION & REGENERATIVE MEDICINE SECTION
MUSCULOSKELETAL, REHABILITATION & REGENERATIVE MEDICINE SECTION
Document Type
Report
Author
Source
Pain Medicine. May 2021, Vol. 22 Issue 5, p1116, 11 p.
Subject
Language
English
ISSN
1526-2375
Abstract
Introduction Knee osteoarthritis is one of the leading causes of global disability [1]. It is associated with chronic knee pain and joint stiffness. There are several conservative treatments in the [...]
Objective. Compare the effectiveness of genicular nerve blockade (GNB) using classical anatomical targets (CT) versus revised targets (RT) in patients suffering from chronic knee osteoarthritis pain. Design. Double-blinded randomized controlled trial. Setting. Pain medicine center of a teaching hospital. Methods. We randomly assigned 55 patients with chronic knee osteoarthritis pain to receive a GNB (using a fluid mixture of 2 mL: lidocaine 1% + 20 mg triamcinolone) with either classical targets (CT-group, n=28) or revised targets (RT-group, n=27). Numeric rating pain scale (NRS), Oxford knee score (OKS), Western Ontario and McMaster Universities osteoarthritis index score (WOMAC), Quantitative analgesic questionnaire (QAQ) and global perceived effects were assessed at baseline, and at 1-hour, 24-hours, 1, 4, and 12 weeks post-intervention. Results. The RT-group showed greater reduction in NRS mean score at 1-hour post-intervention (2.4 [+ or -] 2.1 vs 0.4 [+ or -] 0.9, 95% confidence interval (CI) [.0-.8] vs [1.6-3.2], P Key words: Knee Pain; Injection; Anatomical Landmarks; Radiofrequency Ablation
Objective. Compare the effectiveness of genicular nerve blockade (GNB) using classical anatomical targets (CT) versus revised targets (RT) in patients suffering from chronic knee osteoarthritis pain. Design. Double-blinded randomized controlled trial. Setting. Pain medicine center of a teaching hospital. Methods. We randomly assigned 55 patients with chronic knee osteoarthritis pain to receive a GNB (using a fluid mixture of 2 mL: lidocaine 1% + 20 mg triamcinolone) with either classical targets (CT-group, n=28) or revised targets (RT-group, n=27). Numeric rating pain scale (NRS), Oxford knee score (OKS), Western Ontario and McMaster Universities osteoarthritis index score (WOMAC), Quantitative analgesic questionnaire (QAQ) and global perceived effects were assessed at baseline, and at 1-hour, 24-hours, 1, 4, and 12 weeks post-intervention. Results. The RT-group showed greater reduction in NRS mean score at 1-hour post-intervention (2.4 [+ or -] 2.1 vs 0.4 [+ or -] 0.9, 95% confidence interval (CI) [.0-.8] vs [1.6-3.2], P Key words: Knee Pain; Injection; Anatomical Landmarks; Radiofrequency Ablation