부산대학교 도서관

Toxoplasmosis serodiagnosis was analyzed in the Instituto de Medicina Tropical in Caracas during 1999-2013. Subjects for toxoplasmosis diagnosis were grouped into five categories: pregnancy, human immunodeficiency virus (HIV)/acquired immune deficiency syndrome, ocular pathology, lymphadenopathy, and others. Testing for specific anti-Toxoplasma IgM/IgG antibodies, as well as IgG avidity, was performed. Analysis of 68,622 individuals resulted in an overall prevalence of 50.9%, with 50.9% in pregnant women, 63.8% in patients with eye lesions, 53.1% in HIV-positive individuals, 33.3% in patients with lymphadenopathy, and 49% in other individuals. Toxoplasma gondii infection in pregnant women aged [less than or equal to] 15 years was 32%, which increased to 64% in the middle age category. Diagnostic tests detected 54 recent infections in pregnant women and their follow-up showed no congenital infection. The present age-related and comorbidity prevalence data should be used to design control measures to prevent congenital transmission, coinfection in immunosuppressed patients, and eye lesions in children. KEYWORDS: toxoplasmosis, IgG avidity, pregnancy, HIV, Venezuela
Introduction Toxoplasmosis is a parasitic zoonosis that is caused by the intracellular protozoan Toxoplasma gondii, which can invade any cell type and many species of mammals and birds. (1) At [...]