KOR

e-Article

Transient EDTA‐dependent pseudothrombocytopenia and ulcerative colitis recurrence during chemotherapy: A case of misleading platelet count results attributable to a laboratory artifact
Document Type
article
Source
Clinical Case Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Subject
autoimmune disease
delayed treatment
laboratory artifact
misleading diagnosis
transient EDTA‐dependent pseudothrombocytopenia
Medicine
Medicine (General)
R5-920
Language
English
ISSN
2050-0904
Abstract
Key Clinical Message EDTA‐dependent pseudothrombocytopenia as well as myelosuppression should be suspected when thrombocytopenia occurs in patients with autoimmune disease during chemotherapy. Abstract A patient with pancreatic cancer and ulcerative colitis developed transient ethylenediaminetetraacetic acid (EDTA)‐dependent pseudothrombocytopenia with exacerbation of ulcerative colitis during chemotherapy. Unfortunately, pseudothrombocytopenia could not be immediately detected because thrombocytopenia was masked by a reasonable time course of adverse events associated with chemotherapy and ulcerative colitis recurrence. When thrombocytopenia occurs during chemotherapy, especially in patients with autoimmune diseases, EDTA‐dependent pseudothrombocytopenia and bone marrow suppression caused by anti‐cancer agents should be suspected.