e-Article
Expert consensus on microtransplant for acute myeloid leukemia in elderly patients -report from the international microtransplant interest group
Document Type
article
Author
Huisheng Ai; Nelson J. Chao; David A. Rizzieri; Xiaojun Huang; Thomas R. Spitzer; Jianxiang Wang; Mei Guo; Armand Keating; Elizabeth F. Krakow; Didier Blaise; Jun Ma; Depei Wu; John Reagan; Usama Gergis; Rafael F. Duarte; Preet M. Chaudhary; Kaixun Hu; Changlin Yu; Qiyun Sun; Ephraim Fuchs; Bo Cai; Yajing Huang; Jianhui Qiao; David Gottlieb; Kirk R. Schultz; Mingyao Liu; Xiequn Chen; Wenming Chen; Jianmin Wang; Xiaohui Zhang; Jianyong Li; He Huang; Zimin Sun; Fei Li; Linhua Yang; Liansheng Zhang; Lijuan Li; Kaiyan Liu; Jie Jin; Qifa Liu; Daihong Liu; Chunji Gao; Chuanbo Fan; Li Wei; Xi Zhang; Liangding Hu; Weijing Zhang; Yuyang Tian; Weidong Han; Jun Zhu; Zhijian Xiao; Daobin Zhou; Bolong Zhang; Yongqian Jia; Yongqing Zhang; Xiaoxiong Wu; Xuliang Shen; Xuzhang Lu; Xinrong Zhan; Xiuli Sun; Yi Xiao; Jingbo Wang; Xiaodong Shi; Bo Zheng; Jieping Chen; Banghe Ding; Zhao Wang; Fan Zhou; Mei Zhang; Yizhuo Zhang; Jie Sun; Bing Xia; Baoan Chen; Liangming Ma
Source
Heliyon, Vol 9, Iss 4, Pp e14924- (2023)
Subject
Language
English
ISSN
2405-8440
Abstract
Recent studies have shown that microtransplant (MST) could improve outcome of patients with elderly acute myeloid leukemia (EAML). To further standardize the MST therapy and improve outcomes in EAML patients, based on analysis of the literature on MST, especially MST with EAML from January 1st, 2011 to November 30th, 2022, the International Microtransplant Interest Group provides recommendations and considerations for MST in the treatment of EAML. Four major issues related to MST for treating EAML were addressed: therapeutic principle of MST (1), candidates for MST (2), induction chemotherapy regimens (3), and post-remission therapy based on MST (4). Others included donor screening, infusion of donor cells, laboratory examinations, and complications of treatment.