e-Article
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’
Document Type
article
Author
David S. Fischer; Meshal Ansari; Karolin I. Wagner; Sebastian Jarosch; Yiqi Huang; Christoph H. Mayr; Maximilian Strunz; Niklas J. Lang; Elvira D’Ippolito; Monika Hammel; Laura Mateyka; Simone Weber; Lisa S. Wolff; Klaus Witter; Isis E. Fernandez; Gabriela Leuschner; Katrin Milger; Marion Frankenberger; Lorenz Nowak; Katharina Heinig-Menhard; Ina Koch; Mircea G. Stoleriu; Anne Hilgendorff; Jürgen Behr; Andreas Pichlmair; Benjamin Schubert; Fabian J. Theis; Dirk H. Busch; Herbert B. Schiller; Kilian Schober
Source
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.”