e-Article
An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data
Document Type
article
Author
Source
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Genome-wide chromosome conformation capture has helped us identify features of genome topology influencing biology but requires careful statistical analysis. Here the authors present HiC-DC, a bioinformatics method that can detect statistically significant regulatory interactions.