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e-Article

Community-acquired Staphylococcus aureus bacteriuria: a warning microbiological marker for infective endocarditis?
Document Type
article
Source
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-5 (2019)
Subject
Bacteriuria
Staphylococcus aureus
Bacterial endocarditis
Emergency department
Bacteremia
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1471-2334
Abstract
Abstract Background Urinary tract infection (UTI) is frequently diagnosed in the Emergency Department (ED). Staphylococcus aureus (SA) is an uncommon isolate in urine cultures (0.5–6% of positive urine cultures), except in patients with risk factors for urinary tract colonization. In the absence of risk factors, community-acquired SA bacteriuria may be related to deep-seated SA infection including infective endocarditis. We hypothesized that SA bacteriuria could be a warning microbiological marker of unsuspected infective endocarditis in the ED. Methods This is a retrospective chart review of consecutive adult patients between December 2005 and February 2018. All patients admitted in the ED with both SA bacteriuria (104 CFU/ml SA isolated from a single urine sample) and SA bacteremia, without risk factors for UT colonization (i.e.,