e-Article
Evaluation of HE4 as a prognostic biomarker in uterine cervical cancer
Document Type
article
Author
Source
Cancer Treatment and Research Communications, Vol 34, Iss , Pp 100672- (2023)
Subject
Language
English
ISSN
2468-2942
Abstract
Introduction: Uterine cervical cancer (UCC) is the fourth most common health problem worldwide among women. Currently available biomarkers CA125, CA199, and CEA for diagnosis or prognostic evaluation of UCC have not got widespread acceptance. Method: Whole blood samples of 64 patients with UCC were collected along with 63 healthy females and tested for serum levels of HE4 (sHE4). A cut-off value for positive result 64.0 pmol/L was set. Statistical analysis of different clinical variables was done. Result: Serum level of HE4 has a significant role in the diagnosis of uterine cervical cancer. Its level increases with age, higher parity (P