e-Article
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer
Document Type
article
Author
Neha Singh; Varune R. Ramnarine; Jin H. Song; Ritu Pandey; Sathish K. R. Padi; Mannan Nouri; Virginie Olive; Maxim Kobelev; Koichi Okumura; David McCarthy; Michelle M. Hanna; Piali Mukherjee; Belinda Sun; Benjamin R. Lee; J. Brandon Parker; Debabrata Chakravarti; Noel A. Warfel; Muhan Zhou; Jeremiah J. Bearss; Ewan A. Gibb; Mohammed Alshalalfa; R. Jefferey Karnes; Eric J. Small; Rahul Aggarwal; Felix Feng; Yuzhuo Wang; Ralph Buttyan; Amina Zoubeidi; Mark Rubin; Martin Gleave; Frank J. Slack; Elai Davicioni; Himisha Beltran; Colin Collins; Andrew S. Kraft
Source
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Elevated expression of long noncoding RNA H19 is seen in clinical samples of neuroendocrine prostate cancer (PCa). Here the authors show H19 promotes plasticity from luminal to neuroendocrine by epigenetic reprogramming.