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e-Article

Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
Document Type
article
Source
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-5 (2020)
Subject
Carboplatin
Desensitisation
Drug hypersensitivity
Omalizumab
Immunologic diseases. Allergy
RC581-607
Language
English
ISSN
2045-7022
Abstract
Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.