e-Article
Epidemiological characterization of SARS-CoV-2 variants in children over the four COVID-19 waves and correlation with clinical presentation
Document Type
article
Author
Claudia Alteri; Rossana Scutari; Valentino Costabile; Luna Colagrossi; Katia Yu La Rosa; Emanuele Agolini; Valentina Lanari; Sara Chiurchiù; Lorenza Romani; Anna Hermine Markowich; Paola Bernaschi; Cristina Russo; Antonio Novelli; Stefania Bernardi; Andrea Campana; Alberto Villani; Carlo Federico Perno
Source
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract Since the start of SARS-CoV-2 pandemic, children aged ≤ 12 years have always been defined as underrepresented in terms of SARS-CoV-2 infections’ frequency and severity. By correlating SARS-CoV-2 transmission dynamics with clinical and virological features in 612 SARS-CoV-2 positive patients aged ≤ 12 years, we demonstrated a sizeable circulation of different SARS-CoV-2 lineages over the four pandemic waves in paediatric population, sustained by local transmission chains. Age