e-Article
Persistence of Inoue-Melnick virus and antibody in cerebrospinal fluid
Document Type
Article
Author
Source
Journal of Clinical Microbiology; October 1985, Vol. 22 Issue: 4 p651-653, 3p
Subject
Language
ISSN
00951137; 1098660X
Abstract
Serial cerebrospinal fluid samples were obtained from 14 multiple sclerosis patients over a period of several months and were tested under code for Inoue-Melnick virus. In five of the positive patients, virus was present in 28 of 32 specimens collected over a period of 2 to 5 months. Four patients, from whom a total of 34 specimens were taken, yielded only a single isolate each. Five patients contributed 28 specimens, all of which were negative. In six patients (three virus positive and three virus negative), neutralizing antibody was detected in serum and in cerebrospinal fluid.