e-Article
Intravitreal Delivery of rAAV2tYF-CB-hRS1 Vector for Gene Augmentation Therapy in Patients with X-Linked Retinoschisis
Document Type
Article
Author
Pennesi, Mark Edward; Yang, Paul; Birch, David G.; Weng, Christina Y.; Moore, Anthony T.; Iannaccone, Alessandro; Comander, Jason I.; Jayasundera, Thiran; Chulay, Jeffrey; Chulay, Jeffrey; Halliman, Deanine; Feinsod, Matthew; Pennesi, Mark; Yang, Paul; Birch, David; Bennett, Lea; Weng, Christina Y.; Scholle, Tahira; Channa, Roomasa; Baker, Laura; Stewart, Jay; Moore, Anthony; Iannaccone, Alessandro; Mettu, Priyatham; Vajzovic, Lejla; Jayasundera, K. Thiran; Comander, Jason; Bressler, Neil; Lam, Byron
Source
Ophthalmology Retina; December 2022, Vol. 6 Issue: 12 p1130-1144, 15p
Subject
Language
ISSN
24687219; 24686530
Abstract
To evaluate the safety and efficacy of rAAV2tYF-CB-hRS1, a recombinant adeno-associated virus vector expressing retinoschisin (RS1), in individuals with retinal disease caused by mutations in the RS1gene.