KOR

e-Article

Coronary artery disease: 'gout' in the artery?
Document Type
Article
Source
European Heart Journal; 7/21/2021, Vol. 42 Issue 28, p2761-2764, 4p
Subject
ARTHRITIS
URIC acid
PURINE nucleotides
KIDNEY stones
CYTOKINES
Language
ISSN
0195668X
Abstract
The article presents the discussion on gout becoming a more widespread type of chronic inflammatory arthritis. Topics include uric acid which being a natural product such as the metabolic breakdown of purine nucleotides either from endogenous or dietary sources; leading to acute episodes of joint inflammation and kidney stones; and inflammatory cascade leading to the release of various inflammatory cytokines, chemotactic factors, and lysosomal enzymes.