KOR

e-Article

Carbohydrate arrays as tools for research and diagnostics.
Document Type
Article
Source
Chemical Society Reviews. Jun2008, Vol. 37 Issue 7, p1414-1422. 9p.
Subject
*ORGANIC compounds
*NUCLEIC acids
*RNA
*MICROORGANISMS
Language
ISSN
0306-0012
Abstract
In a very short time, carbohydrate microarrays have become important tools to investigate binding events that involve sugars. High throughput analysis of carbohydrate interactions with a wide range of binding partners, including proteins, RNA, whole cells and viruses, can be performed. Questions ranging from simple binding events to in-depth kinetic analysis can be addressed. This tutorial review summarizes methods to produce carbohydrate microarrays as well as their use. Some selected examples illustrate applications and the potential that these tools hold. [ABSTRACT FROM AUTHOR]