e-Article
Could knee inflammatory synovitis be induced by pembrolizumab?
Document Type
Article
Author
Source
Subject
*KNEE
*MELANOMA
*MONOCLONAL antibodies
*SYNOVITIS
*DIAGNOSIS
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*
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*
Language
ISSN
1078-1552
Abstract
Pembrolizumab, a selective anti-PD-1 humanized monoclonal antibody, reactivates T cells to fight cancer. Immune-related adverse events such as autoimmune colitis, pneumonitis, hepatitis, nephritis, hypophysitis, and thyroiditis may occur during, or weeks to months after therapy. Pemprolizumab-induced synovitis is rarely reported. With the wide use of immunotherapy to treat cancers, physicians need to be aware of this rare immune-related adverse event and provide immediate treatment to avoid permanent joint damage. [ABSTRACT FROM AUTHOR]