e-Article
Head-to-Head Comparison of FDG and Radiolabeled FAPI PET: A Systematic Review of the Literature.
Document Type
Article
Author
Guglielmo, Priscilla; Alongi, Pierpaolo; Baratto, Lucia; Abenavoli, Elisabetta; Buschiazzo, Ambra; Celesti, Greta; Conte, Miriam; Filice, Rossella; Gorica, Joana; Jonghi-Lavarini, Lorenzo; Lanzafame, Helena; Laudicella, Riccardo; Librando, Maria; Linguanti, Flavia; Mattana, Francesco; Miceli, Alberto; Olivari, Laura; Piscopo, Leandra; Romagnolo, Cinzia; Santo, Giulia
Source
Subject
*PERITONEAL cancer
*RADIOPHARMACEUTICALS
*POSITRON emission tomography
*NUCLEAR medicine
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Language
ISSN
2075-1729
Abstract
FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [18F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-head comparison had been performed to explore the potential utility of FAPI tracers in clinical practice. FAPI-based radiopharmaceuticals have shown promising results globally, in particular in detecting peritoneal carcinomatosis, but studies with wider populations are needed to better understand all the advantages of these new radiopharmaceuticals. [ABSTRACT FROM AUTHOR]