e-Article
Rescue treatment of severe lupus myocarditis and proliferative lupus nephritis with immunoadsorption.
Document Type
Case Study
Author
Source
Subject
*IMMUNOADSORPTION
*LUPUS nephritis
*MYOCARDITIS
*MEDICAL care
*THERAPEUTICS
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Language
ISSN
0770-3198
Abstract
We report a patient with severe systemic lupus erythematosus (SLE) with myocarditis and proliferative glomerulonephritis successfully treated with immunoadsorption (IA) and intravenous immunoglobulins (IVIG) as an addition to cyclophosphamide. Nine IA procedures using Globaffin adsorber system (Fresenius Medical Care, Bad Homburg, Germany), were performed mostly every other day (with 20 grams of IVIG on the days without IA, a total of 9 applications), as well as three SCUF procedures prior to IA sessions. In our patient, IA reverted the detrimental course of lupus myocarditis in a patient that had previously been started on a standard cyclophosphamide regimen. [Extracted from the article]