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e-Article

Novel Bio-fabrication Modelling Approach from Marine Sources: Synthesis, Characterization and its Composite Formulations.
Document Type
Article
Source
Trends in Biomaterials & Artificial Organs. 2022 Special Issue, Vol. 36, p59-66. 8p.
Subject
*TISSUE engineering
*SILVER nanoparticles
*MINERALS
*WOUND healing
*SILVER ions
*SEASHELLS
*MEDICAL care
Language
ISSN
0971-1198
Abstract
Hydroxyapatite, a bone mineral was extracted from different seashell species by hydrothermal method and investigated by SEM-EDX, FTIR, TGA, DSC, XRD, and EPR analysis. Amongst, the seashell Dallarca subrostata was chosen for composite preparation by incorporating chitosan and silver nanoparticles which could be used as fillers and films for wound healing applications. Silver ions doped HA were examined using EPR for better biocompatibility. These findings further aim to create a patient-specific implant using 3D modelling. It paves the way for the potential applications as a pre-operative surgical planning procedure and a better point of health care. Further, the biominerals extracted would act as a source for the fabrication of designs and thereafter 3D modelling for investigation. It also rectifies tissue engineering challenges faced so far. [ABSTRACT FROM AUTHOR]