e-Article
Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020.
Document Type
Journal Article
Author
Source
Subject
*HEMAGGLUTININ
*INFLUENZA
*VIRUS diseases
*VIRUSES
*DRUG monitoring
*PROTEINS
*ANTIVIRAL agents
*IMMUNOLOGICAL adjuvants
*GLYCOSIDASES
*DRUG resistance in microorganisms
*INFLUENZA A virus, H1N1 subtype
*OSELTAMIVIR
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Language
ISSN
1080-6040
Abstract
Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses. [ABSTRACT FROM AUTHOR]