e-Article
Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.
Document Type
Article
Author
Source
Subject
*LYMPHOMA risk factors
*ENDOCRINE diseases
*ENDOCRINE disruptors
*OCCUPATIONAL diseases
*B cell lymphoma
*PUBLIC health
*DISEASE risk factors
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Language
ISSN
0007-0920
Abstract
Background:Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.Methods:We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study.Results:Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women.Conclusions:Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes. [ABSTRACT FROM AUTHOR]