e-Article
Diagnosis of carmine allergy using carminic acid solves interference of house dust mite and crustacean cross‐reactivity.
Document Type
Article
Author
Source
Subject
*HOUSE dust mites
*ALLERGIES
*CRUSTACEA
*CROSS reactions (Immunology)
*DIAGNOSIS
*URTICARIA
*ATOPY
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Language
ISSN
0954-7894
Abstract
Keywords: anaphylaxis; carmine; cochineal lice; cross-reactivity; Dermatophagoides pteronyssinus; food hypersensitivity; specific IgE EN anaphylaxis carmine cochineal lice cross-reactivity Dermatophagoides pteronyssinus food hypersensitivity specific IgE 1225 1229 5 10/13/22 20221001 NES 221001 Key messages Cochineal lice sIgE testing is a weak predictor for carmine allergy due to irrelevant cross-reactivity. ONLY IN PRIMARY CARMINE ALLERGY, CARMINIC ACID CAUSES BASOPHIL DEGRANULATION Six patients with cochineal lice sIgE were available for BAT experiments, including COCH1 (Figure 1D-H) and five had a positive BAT for HDM (Figure 1E). Diagnosis of carmine allergy using carminic acid solves interference of house dust mite and crustacean cross-reactivity These experiments supported a carminic acid allergy in patient COCH1, whereas other patients demonstrated clinically irrelevant cross-reactivity due to HDM and/or crustacean sensitization. [Extracted from the article]