부산대학교 도서관

Salim Neto, SC; Pezzopane, JEM; da Silva, GF; Ferreira, RLC; Martínez, JRM; Machuca, MAH

Journal of Tropical Forest Science, 2021 Oct 01. 33(4), 444-454.

Dijkstra KK; Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Oncode Institute, Utrecht, the Netherlands. Electronic address: k.dijkstra@nki.nl.; Vendramin R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Tumor ImmunoGenomics and Immunosurveillance Laboratory, University College London Cancer Institute, University College London, London, UK.; Karagianni D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Immunology Unit, Immune Regulation and Tumor Immunotherapy Group, Research Department of Haematology, University College London Cancer Institute, London, UK.; Witsen M; Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands.; Gálvez-Cancino F; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Immunology Unit, Immune Regulation and Tumor Immunotherapy Group, Research Department of Haematology, University College London Cancer Institute, London, UK; Immune Regulation Laboratory, Centre for Immuno-Oncology, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Foster KA; Cancer Immunology Unit, Immune Regulation and Tumor Immunotherapy Group, Research Department of Haematology, University College London Cancer Institute, London, UK.; Barbè V; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Hynds RE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Epithelial Cell Biology in ENT Research (EpiCENTR) Group, Developmental Biology and Cancer Department, Great Ormond Street UCL Institute of Child Health, University College London, London, UK.; Pearce DR; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Martínez-Ruiz C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Black JRM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Augustine M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Tumor ImmunoGenomics and Immunosurveillance Laboratory, University College London Cancer Institute, University College London, London, UK; Division of Medicine, University College London, London, UK.; Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Department of Cellular Pathology, University College London Hospital, London, UK.; Liu LL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Saghafinia S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; van de Haar J; Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands.; Veeriah S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Naceur-Lombardelli C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Toncheva A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Bola SK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Immunology Unit, Immune Regulation and Tumor Immunotherapy Group, Research Department of Haematology, University College London Cancer Institute, London, UK.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK; Department of Medical Oncology, University College London Hospitals, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Tumor ImmunoGenomics and Immunosurveillance Laboratory, University College London Cancer Institute, University College London, London, UK.; Reading JL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Pre-Cancer Immunology Laboratory, University College London Cancer Institute, London, UK.; Chain B; University College London Cancer Institute, London, UK; Division of Infection and Immunity, University College London, London, UK.; Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Cancer Immunology Unit, Immune Regulation and Tumor Immunotherapy Group, Research Department of Haematology, University College London Cancer Institute, London, UK. Electronic address: s.quezada@ucl.ac.uk.; Voest EE; Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands. Electronic address: e.voest@nki.nl.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK; Department of Medical Oncology, University College London Hospitals, London, UK. Electronic address: charles.swanton@crick.ac.uk.

Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

SC Salim Neto; JEM Pezzopane; GF da Silva; RLC Ferreira; JRM Martínez; MAH Machuca

JOURNAL OF TROPICAL FOREST SCIENCE. 33:444-454

Ng KW; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Boumelha J; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Enfield KSS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Almagro J; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.; Cha H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Queensland, Australia.; Sivakumar M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Young G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Bioinformatics and Biostatistics Facility, The Francis Crick Institute, London, UK.; Molina-Arcas M; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; de Carné Trécesson S; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Anastasiou P; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Fendler A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Kim H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Shim S; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Faulkner N; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Attig J; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Magno N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Behrens A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.; Cancer Stem Cell Laboratory, Institute of Cancer Research, London, UK.; Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK.; CRUK Convergence Science Centre, Imperial College, London, UK.; Yousaf N; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Lung Unit, The Royal Marsden Hospital, London, UK.; Popat S; Lung Unit, The Royal Marsden Hospital, London, UK.; Division of Clinical Studies, The Institute of Cancer Research, London, UK.; Hackshaw A; Cancer Research UK and University College London Cancer Trials Centre, London, UK.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Larkin J; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK.; Lee SH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.; Downward J; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK. julian.downward@crick.ac.uk.; Kassiotis G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK. george.kassiotis@crick.ac.uk.; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK. george.kassiotis@crick.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; In Process

Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, the Francis Crick Institute, London, UK.; Jones TP; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Litovchenko M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, the Francis Crick Institute, London, UK.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, the Francis Crick Institute, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.

Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

Frankell, AM; Dietzen, M; Al Bakir, M; Lim, EL; Karasaki, T; Ward, S; Veeriah, S; Colliver, E; Huebner, A; Bunkum, A; Hill, MS; Grigoriadis, K; Moore, DA; Black, JRM; Liu, WK; Thol, K; Pich, O; Watkins, TBK; Naceur-Lombardelli, C; Cook, DE; Salgado, R; Wilson, GA; Bailey, C; Angelova, M; Bentham, R; Martínez-Ruiz, C; Abbosh, C; Nicholson, AG; Le Quesne, J; Biswas, D; Rosenthal, R; Puttick, C; Hessey, S; Lee, C; Prymas, P; Toncheva, A; Smith, J; Xing, W; Nicod, J; Price, G; Kerr, KM; Naidu, B; Middleton, G; Blyth, KG; Fennell, DA; Forster, MD; Lee, SM; Falzon, M; Hewish, M; Shackcloth, MJ; Lim, E; Benafif, S; Russell, P; Boleti, E; Krebs, MG; Lester, JF; Papadatos-Pastos, D; Ahmad, T; Thakrar, RM; Lawrence, D; Navani, N; Janes, SM; Dive, C; Blackhall, FH; Summers, Y; Cave, J; Marafioti, T; Herrero, J; Quezada, SA; Peggs, KS; Schwarz, RF; Van Loo, P; Miedema, DM; Birkbak, NJ; Hiley, CT; Hackshaw, A; Zaccaria, S; Bajaj, A; Nakas, A; Sodha-Ramdeen, A; Ang, K; Tufail, M; Chowdhry, MF; Scotland, M; Boyles, R; Rathinam, S; Wilson, C; Marrone, D; Dulloo, S; Matharu, G; Shaw, JA; Riley, J; Primrose, L; Cheyne, H; Khalil, M; Richardson, S; Cruickshank, T; Gilbert, K

Steering Committee; Alderson, D; Bundred, J; RPT, Evans; Gossage, J; Griffiths, EA; Jefferies, B; Kamarajah, SK; McKay, S; Mohamed, I; Nepogodiev, D; Siaw- Acheampong, K; Singh, P; van Hillegersberg, R; Vohra, R; Wanigasooriya, K; Whitehouse, T.; National Leads; Gjata, A; Moreno, JI; Takeda, FR; Kidane, B; Guevara Castro, R; Harustiak, T; Bekele, A; Kechagias, A; Gockel, I; Kennedy, A; Da Roit, A; Bagajevas, A; Azagra, JS; Mahendran, HA; Mejía-Fernández, L; Wijnhoven, BPL; El Kafsi, J; Sayyed, RH; Sousa, M; Sampaio, AS; Negoi, I; Blanco, R; Wallner, B; Schneider, PM; Hsu, PK; Isik, A; Site Leads; Gananadha, S; Wills, V; Devadas, M; Duong, C; Talbot, M; Hii, MW; Jacobs, R; Andreollo, NA; Johnston, B; Darling, G; Isaza-Restrepo, A; Rosero, G; Arias- Amézquita, F; Raptis, D; Gaedcke, J; Reim, D; Izbicki, J; Egberts, JH; Dikinis, S; Kjaer, DW; Larsen, MH; Achiam, MP; Saarnio, J; Theodorou, D; Liakakos, T; Korkolis, DP; Robb, WB; Collins, C; Murphy, T; Reynolds, J; Tonini, V; Migliore, M; Bonavina, L; Valmasoni, M; Bardini, R; Weindelmayer, J; Terashima, M; White, RE; Alghunaim, E; Elhadi, M; Leon-Takahashi, AM; Medina-Franco, H; Lau, PC; Okonta, KE; Heisterkamp, J; Rosman, C; van Hillegersberg, R; Beban, G; Babor, R; Gordon, A; Rossaak, JI; Pal, KMI; Qureshi, AU; Naqi, SA; Syed, AA; Barbosa, J; Vicente, CS; Leite, J; Freire, J; Casaca, R; Costa, RCT; Scurtu, RR; Mogoanta, SS; Bolca, C; Constantinoiu, S; Sekhniaidze, D; Bjelović, M; So, JBY; Gačevski, G; Loureiro, C; Pera, M; Bianchi, A; Moreno Gijón, M; Martín Fernández, J; Trugeda Carrera, MS; Vallve-Bernal, M; Cítores Pascual, MA; Elmahi, S; Halldestam, I; Hedberg, J; Mönig, S; Gutknecht, S; Tez, M; Guner, A; Tirnaksiz, MB; Colak, E; Sevinç, B; Hindmarsh, A; Khan, I; Khoo, D; Byrom, R; Gokhale, J; Wilkerson, P; Jain, P; Chan, D; Robertson, K; Iftikhar, S; Skipworth, R; Forshaw, M; Higgs, S; Gossage, J; Nijjar, R; Viswanath, YKS; Turner, P; Dexter, S; Boddy, A; Allum, WH; Oglesby, S; Cheong, E; Beardsmore, D; Vohra, R; Maynard, N; Berrisford, R; Mercer, S; Puig, S; Melhado, R; Kelty, C; Underwood, T; Dawas, K; Lewis, W; Al-Bahrani, A; Bryce, G; Thomas, M; Arndt, AT; Palazzo, F; Meguid, RA; Collaborators; Fergusson, J; Beenen, E; Mosse, C; Salim, J; Cheah, S; Wright, T; Cerdeira, MP; McQuillan, P; Richardson, M; Liem, H; Spillane, J; Yacob, M; Albadawi, F; Thorpe, T; Dingle, A; Cabalag, C; Loi, K; Fisher, OM; Ward, S; Read, M; Johnson, M; Bassari, R; Bui, H; Cecconello, I; RAA, Sallum; da Rocha, JRM; Lopes, LR; Tercioti, V, Jr; JDS, Coelho; Ferrer, JAP; Buduhan, G; Tan, L; Srinathan, S; Shea, P; Yeung, J; Allison, F; Carroll, P; Vargas-Barato, F; Gonzalez, F; Ortega, J; Nino-Torres, L; Beltrán-García, TC; Castilla, L; Pineda, M; Bastidas, A; Gómez-Mayorga, J; Cortés, N; Cetares, C; Caceres, S; Duarte, S; Pazdro, A; Snajdauf, M; Faltova, H; Sevcikova, M; Mortensen, PB; Katballe, N; Ingemann, T; Kruhlikava, Morten B, I; Ainswort, AP; Stilling, NM; Eckardt, J; Holm, J; Thorsteinsson, M; Siemsen, M; Brandt, B; Nega, B; Teferra, E; Tizazu, A; Kauppila, JH; Koivukangas, V; Meriläinen, S; Gruetzmann, R; Krautz, C; Weber, G; Golcher, H; Emons, G; Azizian, A; Ebeling, M; Niebisch, S; Kreuser, N; Albanese, G; Hesse, J; Volovnik, L; Boecher, U; Reeh, M; Triantafyllou, S; Schizas, D; Michalinos, A; Balli, E; Mpoura, M; Charalabopoulos, A; Manatakis, DK; Balalis, D; Bolger, J; Baban, C; Mastrosimone, A; McAnena, O; Quinn, A; Ó Súilleabháin, CB; Hennessy, MM; Ivanovski, I; Khizer, H; Ravi, N; Donlon, N; Cervellera, M; Vaccari, S; Bianchini, S; Sartarelli, l; Asti, E; Bernardi, D; Merigliano, S; Provenzano, L; Scarpa, M; Saadeh, L; Salmaso, B; De Manzoni, G; Giacopuzzi, S; La Mendola; R; De Pasqual, CA; Tsubosa, Y; Niihara, M; Irino, T; Makuuchi, R; Ishii, K; Mwachiro, M; Fekadu, A; Odera, A; Mwachiro, E; AlShehab, D; Ahmed, HA; Shebani, AO; Elhadi, A; Elnagar, FA; Elnagar, HF; Makkai-Popa, ST; Wong, LF; Tan, YR; Thannimalai, S; Ho, CA; Pang, WS; Tan, JH; HNL, Basave; Cortés-González, R; Lagarde, SM; van Lanschot, JJB; Cords, C; Jansen, WA; Martijnse, I; Matthijsen, R; Bouwense, S; Klarenbeek, B; Verstegen, M; van Workum, F; Ruurda, JP; van der Sluis, PC; de Maat, M; Evenett, N; Johnston, P; Patel, R; MacCormick, A; Young, M; Smith, B; Ekwunife, C; Memon, AH; Shaikh, K; Wajid, A; Khalil, N; Haris, M; Mirza, ZU; SBA, Qudus; Sarwar, MZ; Shehzadi, A; Raza, A; Jhanzaib, MH; Farmanali, J; Zakir, Z; Shakeel, O; Nasir, I; Khattak, S; Baig, M; Noor, MA; Ahmed, HH; Naeem, A; Pinho, AC; da Silva, R; Bernardes, A; Campos, JC; Matos, H; Braga, T; Monteiro, C; Ramos, P; Cabral, F; Gomes, MP; Martins, PC; Correia, AM; Videira, JF; Ciuce, C; Drasovean, R; Apostu, R; Ciuce, C; Paitici, S; Racu, AE; Obleaga, CV; Beuran, M; Stoica, B; Negoita, Ciubotaru C, V; Cordos, I; Birla, RD; Predescu, D; Hoara, PA; Tomsa, R; Shneider, V; Agasiev, M; Ganjara, I; Gunjić, D; Veselinović, M; Babič, T; Chin, TS; Shabbir, A; Kim, G; Crnjac, A; Samo, H; Díez del Val, 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Annals of Surgery. May 01, 2023 277(5):e1026-e1034

Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Department of Thoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Abbott CW; Personalis Inc., Fremont, CA, USA.; Li B; Personalis Inc., Fremont, CA, USA.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Al Bakir M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Department of Oncology, University College London Hospitals, London, UK.; Liu WK; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Pawlik P; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.; Marinelli D; Department of Experimental Medicine, Sapienza University, Rome, Italy.; Shutkever O; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Murphy C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Liu LY; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Grieco C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Grimes K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Navarro FCP; Personalis Inc., Fremont, CA, USA.; Pyke RM; Personalis Inc., Fremont, CA, USA.; Bartha G; Personalis Inc., Fremont, CA, USA.; Keough KC; Personalis Inc., Fremont, CA, USA.; Dea S; Personalis Inc., Fremont, CA, USA.; Ravi N; Personalis Inc., Fremont, CA, USA.; Lyle J; Personalis Inc., Fremont, CA, USA.; Harris J; Personalis Inc., Fremont, CA, USA.; Brown KD; The Christie NHS Foundation Trust, Manchester, UK; Division of Cancer Sciences, The University of Manchester, Manchester, UK.; Blackhall FH; The Christie NHS Foundation Trust, Manchester, UK; Division of Cancer Sciences, The University of Manchester, Manchester, UK.; Hassani F; University Hospitals of Leicester NHS Trust, Leicester, UK.; Fennell DA; University Hospitals of Leicester NHS Trust, Leicester, UK; University of Leicester, Leicester, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK.; Shaw JA; University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, Leicester, UK.; Abbosh C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; AstraZeneca, Cambridge, UK.; Hackshaw A; Cancer Research UK, UCL Clinical Trials Centre, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Department of Oncology, University College London Hospitals, London, UK; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Early Cancer Institute, University of Cambridge, Cambridge, UK.; Boyle SM; Personalis Inc., Fremont, CA, USA.; Chen RO; Personalis Inc., Fremont, CA, USA.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; Department of Oncology, University College London Hospitals, London, UK. Electronic address: charles.swanton@crick.ac.uk.

Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Hobor S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Department of Medical Oncology, University College London Hospitals, 235 Euston Rd, Fitzrovia, London, NW1 2BU, UK.; Skrzypski M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Department of Medical Oncology, University College London Hospitals, 235 Euston Rd, Fitzrovia, London, NW1 2BU, UK.; Department of Oncology and Radiotherapy, Medical University of Gdańsk, ul. Mariana Smoluchowskiego 17, 80-214, Gdańsk, Poland.; Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Bakker B; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, 9713, the Netherlands.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Markovets A; Oncology Data Science, Oncology R&D, AstraZeneca, Boston, MA, USA.; Dry JR; Late Development, Oncology R&D, AstraZeneca, Boston, MA, USA.; Brown AP; Late Development, Oncology R&D, AstraZeneca, Boston, MA, USA.; van der Aart J; Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.; van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, 9713, the Netherlands.; Spierings D; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, 9713, the Netherlands.; Oukrif D; Research Department of Pathology, University College London Medical School, University Street, London, WC1E 6JJ, UK.; Novelli M; Research Department of Pathology, University College London Medical School, University Street, London, WC1E 6JJ, UK.; Chakrabarti T; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; Rabinowitz AH; Furlong Laboratory, EMBL Meyerhofstraße 1, 69117, Heidelberg, Germany.; Ait Hassou L; European Organization for Research and Treatment of Cancer, Brussels, Belgium.; Litière S; Bioinformatics & Biostatistics; Francis Crick Institute, London, UK.; Kerr DL; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; Tan L; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; Kelly G; Bioinformatics & Biostatistics; Francis Crick Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Renshaw MJ; Advanced Light Microscopy, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Venkatesan S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Hill W; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Wu W; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Downward J; Oncogene Biology Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Chmielecki J; Late Development, Oncology R&D, AstraZeneca, Boston, MA, USA.; Barrett C; Late Development, Oncology R&D, AstraZeneca, Boston, MA, USA.; Litchfield K; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Chew SK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Blakely CM; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; de Bruin EC; Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.; Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, 9713, the Netherlands.; Vousden KH; p53 and Metabolism Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Bivona TG; Department of Medicine, University of California, San Francisco, CA, 94158, USA.; Chan-Zuckerberg Biohub, San Francisco, USA.; Hynds RE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.; Kanu N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK. n.kanu@ucl.ac.uk.; Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK. s.zaccaria@ucl.ac.uk.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK. s.zaccaria@ucl.ac.uk.; Grönroos E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK. Eva.Gronroos@crick.ac.uk.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK. Charles.Swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK. Charles.Swanton@crick.ac.uk.; Department of Medical Oncology, University College London Hospitals, 235 Euston Rd, Fitzrovia, London, NW1 2BU, UK. Charles.Swanton@crick.ac.uk.

Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Martinez-Berumen, I.; Coish, W. A.; Pereg-Barnea, T.

Phys. Rev. B 107, 205110 (2023)

Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Bartha G; Personalis Inc., Fremont, CA, USA.; Abbott CW; Personalis Inc., Fremont, CA, USA.; Boyle SM; Personalis Inc., Fremont, CA, USA.; Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Thoracic Surgery, Respiratory Center, Toranomon Hospital, Tokyo, Japan.; Li B; Personalis Inc., Fremont, CA, USA.; Chen R; Personalis Inc., Fremont, CA, USA.; Harris J; Personalis Inc., Fremont, CA, USA.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Colopi M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Liu WK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Lyle J; Personalis Inc., Fremont, CA, USA.; Navarro FCP; Personalis Inc., Fremont, CA, USA.; Northcott J; Personalis Inc., Fremont, CA, USA.; Pyke RM; Personalis Inc., Fremont, CA, USA.; Hill MS; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bailey C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Colliver EC; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pawlik P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Marinelli D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Experimental Medicine, Sapienza University, Rome, Italy.; Shutkever OG; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Murphy C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Sivakumar M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Shaw JA; Leicester NIHR BRC & University of Leicester, Leicester, UK.; Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK.; Chen RO; Personalis Inc., Fremont, CA, USA.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory., The Francis Crick Institute, London, UK. Charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.swanton@crick.ac.uk.

Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Ripolles-Melchor J; Hospital Universitario Infanta Leonor, Madrid, Spain; Universidad Complutense de Madrid, Madrid, Spain. Electronic address: ripo542@gmail.com.; Abad-Motos A; Hospital Universitario de Donostia, San Sebastian, Spain.; Nieto Moreno E; Hospital Universitario Infanta Leonor, Madrid, Spain; Universidad Complutense de Madrid, Madrid, Spain.; Jerico C; Hospital Universitario Moises Broggi, Sant Joan D'Espí, Spain.; Otero-Martínez I; Hospital Alvaro Cunqueiro de Vigo, Vigo, Spain.; Abdel-Lah Fernández O; Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.; García-Alvarez R; Hospital Universitario 12 Octubre, Madrid, Spain.; Tormos-Pérez MP; Hospital Universitario Vall D'Hebrón, Barcelona, Spain.; Espinosa AV; Froedtert Hospital Medical College of Wisconsin, Milwaukee, WI, United States.; Aldecoa C; Hospital Universitario Río Hortega, Valladolid, Spain.; Abad-Gurumeta A; Hospital Universitario Infanta Leonor, Madrid, Spain; Universidad Complutense de Madrid, Madrid, Spain.; Colomina MJ; Hospital Universitario de Bellvitge, Bellvitge, Spain.; García-Erce JA; Blood and Tissue Bank of Navarra, Servicio Navarro de Salud, Osasunbidea, Pamplona, Spain.

Publisher: Elsevier España Country of Publication: Spain NLM ID: 101778594 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2341-1929 (Electronic) Linking ISSN: 23411929 NLM ISO Abbreviation: Rev Esp Anestesiol Reanim (Engl Ed) Subsets: MEDLINE

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Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Dietzen M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Grigoriadis K; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Liu WK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bailey C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bentham R; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Nicholson AG; Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Pathology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK.; Biswas D; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Lee C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Division of Medicine, University College London, London, UK.; Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Smith J; Scientific Computing, The Francis Crick Institute, London, UK.; Xing W; Scientific Computing, The Francis Crick Institute, London, UK.; Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK.; Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Blyth KG; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK.; Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK.; Hewish M; Royal Surrey Hospital, Royal Surrey Hospitals NHS Foundation Trust, Guilford, UK.; University of Surrey, Guilford, UK.; Shackcloth MJ; Liverpool Heart and Chest Hospital, Liverpool, UK.; Lim E; Academic Division of Thoracic Surgery, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Benafif S; Department of Oncology, University College London Hospitals, London, UK.; Russell P; Princess Alexandra Hospital, The Princess Alexandra Hospital NHS Trust, Harlow, UK.; Boleti E; Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK.; Krebs MG; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Lester JF; Singleton Hospital, Swansea Bay University Health Board, Swansea, UK.; Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK.; Ahmad T; Department of Oncology, University College London Hospitals, London, UK.; Thakrar RM; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK.; Navani N; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK.; Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Marafioti T; Department of Cellular Pathology, University College London Hospitals, London, UK.; Herrero J; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.; Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.; Schwarz RF; Institute for Computational Cancer Biology, Center for Integrated Oncology (CIO), Cancer Research Center Cologne Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany.; Van Loo P; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Miedema DM; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Amsterdam, The Netherlands.; Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hackshaw A; Cancer Research UK and UCL Cancer Trials Centre, London, UK.; Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; PubMed not MEDLINE

Ng KW; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Boumelha J; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Enfield KSS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Almagro J; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.; Cha H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Queensland, Australia.; Sivakumar M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Young G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Bioinformatics and Biostatistics Facility, The Francis Crick Institute, London, UK.; Molina-Arcas M; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; de Carné Trécesson S; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Anastasiou P; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; Fendler A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Kim H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Shim S; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Faulkner N; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Attig J; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Magno N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Behrens A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.; Cancer Stem Cell Laboratory, Institute of Cancer Research, London, UK.; Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK.; CRUK Convergence Science Centre, Imperial College, London, UK.; Yousaf N; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Lung Unit, The Royal Marsden Hospital, London, UK.; Popat S; Lung Unit, The Royal Marsden Hospital, London, UK.; Division of Clinical Studies, The Institute of Cancer Research, London, UK.; Hackshaw A; Cancer Research UK and University College London Cancer Trials Centre, London, UK.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Larkin J; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK.; Lee SH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden Hospital, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.; Downward J; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK. julian.downward@crick.ac.uk.; Kassiotis G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK. george.kassiotis@crick.ac.uk.; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK. george.kassiotis@crick.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Frankell AM; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Dietzen M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Lim EL; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Karasaki T; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Ward S; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bunkum A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Grigoriadis K; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Moore DA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Liu WK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bailey C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Angelova M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bentham R; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Nicholson AG; Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Pathology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK.; Biswas D; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Puttick C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Lee C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Division of Medicine, University College London, London, UK.; Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Smith J; Scientific Computing, The Francis Crick Institute, London, UK.; Xing W; Scientific Computing, The Francis Crick Institute, London, UK.; Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Price G; Department of Medical Oncology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; University of Aberdeen, Aberdeen, UK.; Kerr KM; University of Aberdeen, Aberdeen, UK.; Department of Pathology, Aberdeen Royal Infirmary NHS Grampian, Aberdeen, UK.; Naidu B; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Middleton G; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Blyth KG; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Queen Elizabeth University Hospital, Glasgow, UK.; Fennell DA; University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Forster MD; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Lee SM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Falzon M; Department of Cellular Pathology, University College London Hospitals, London, UK.; Hewish M; Royal Surrey Hospital, Royal Surrey Hospitals NHS Foundation Trust, Guilford, UK.; University of Surrey, Guilford, UK.; Shackcloth MJ; Liverpool Heart and Chest Hospital, Liverpool, UK.; Lim E; Academic Division of Thoracic Surgery, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Benafif S; Department of Oncology, University College London Hospitals, London, UK.; Russell P; Princess Alexandra Hospital, The Princess Alexandra Hospital NHS Trust, Harlow, UK.; Boleti E; Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK.; Krebs MG; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Lester JF; Singleton Hospital, Swansea Bay University Health Board, Swansea, UK.; Papadatos-Pastos D; Department of Oncology, University College London Hospitals, London, UK.; Ahmad T; Department of Oncology, University College London Hospitals, London, UK.; Thakrar RM; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Lawrence D; Department of Thoracic Surgery, University College London Hospital NHS Trust, London, UK.; Navani N; Department of Thoracic Medicine, University College London Hospitals, London, UK.; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Janes SM; Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.; Dive C; Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University of Manchester, Manchester, UK.; Blackhall FH; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Summers Y; Division of Cancer Sciences, The University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.; Cave J; Department of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Marafioti T; Department of Cellular Pathology, University College London Hospitals, London, UK.; Herrero J; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Quezada SA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.; Peggs KS; Department of Haematology, University College London Hospitals, London, UK.; Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK.; Schwarz RF; Institute for Computational Cancer Biology, Center for Integrated Oncology (CIO), Cancer Research Center Cologne Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany.; Van Loo P; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Miedema DM; LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Amsterdam, The Netherlands.; Birkbak NJ; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Hiley CT; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hackshaw A; Cancer Research UK and UCL Cancer Trials Centre, London, UK.; Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. charles.swanton@crick.ac.uk.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. charles.swanton@crick.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Demeulemeester J; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Integrative Cancer Genomics Laboratory, Department of Oncology, KU Leuven, Leuven, Belgium.; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.; Larose Cadieux E; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Medical Genomics, University College London Cancer Institute, London, UK.; Thol K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Jones TP; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Cubitt L; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Athanasopoulou F; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Castignani C; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Medical Genomics, University College London Cancer Institute, London, UK.; Dietzen M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Al Bakir M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Tanić M; Medical Genomics, University College London Cancer Institute, London, UK.; Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Al-Rashed AM; Centre for Nephrology, Division of Medicine, University College London, London, UK.; Lang D; Scientific Computing STP, Francis Crick Institute, London, UK.; Clements J; Scientific Computing STP, Francis Crick Institute, London, UK.; Cook DE; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Rosenthal R; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Wilson GA; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; de Carné Trécesson S; Oncogene Biology Laboratory, The Francis Crick Institute, London, UK.; East P; Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.; Kanu N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.; Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.; Beck S; Medical Genomics, University College London Cancer Institute, London, UK.; Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Medical Oncology, University College London Hospitals, London, UK.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.Swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute and University College London Cancer Institute, London, UK. Charles.Swanton@crick.ac.uk.; Department of Medical Oncology, University College London Hospitals, London, UK. Charles.Swanton@crick.ac.uk.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Al-Sawaf O; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Weiss J; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Department of Diagnostic and Interventional Radiology, University Freiburg, Freiburg, Germany.; Skrzypski M; Department of Oncology and Radiotherapy, Medical University of Gdańsk, Gdańsk, Poland.; Lam JM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Department of Oncology, University College London Hospitals, London, UK.; Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Zambrana F; Infanta Sofía University Hospital, Madrid, Spain.; Kidd AC; Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Watkins TBK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Sokač M; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Collins S; Early Clinical Development, Pfizer UK Ltd, Cambridge, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Magno N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Prymas P; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Jayanth N; Cancer Research UK & UCL Cancer Trials Centre, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Australia.; Bridge CP; MGH & BWH Center for Clinical Data Science, Boston, MA, USA.; Christiani DC; Department of Medicine, Massachusetts General Hospital/Harvard Medicine School, and Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Mak RH; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Bay C; Department of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA, USA.; Rosenthal M; Department of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA, USA.; Sattar N; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.; Welsh P; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.; Liu Y; Department of Genetics, Harvard Medical School, Boston, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, USA.; Perrimon N; Department of Genetics, Harvard Medical School, Boston, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, USA.; Popuri K; Department of Computer Science, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Burnaby, Canada.; Beg MF; School of Engineering Science, Simon Fraser University, Burnaby, British Colombia, Canada.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.; Breen DM; Internal Medicine Research Unit, Pfizer, Cambridge, MA, USA.; O'Rahilly S; Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK.; Birkbak NJ; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Aerts HJWL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Radiology and Nuclear Medicine, CARIM & GROW, Maastricht University, Maastricht, The Netherlands.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. Charles.swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.swanton@crick.ac.uk.

Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Moore DA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Cellular Pathology, University College London Hospitals, London, UK.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Toncheva A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Magno N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Huebner A; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Hill MS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Zhai H; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Gimeno-Valiente F; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Saghafinia S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Kanu N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Dietzen M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Pich O; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Lim EL; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Biswas D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Campbell BB; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Lee C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Colliver E; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Enfield KSS; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Hessey S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Hiley CT; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Zaccaria S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.; Birkbak NJ; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Cadieux EL; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Medical Genomics, University College London Cancer Institute, London, UK.; Demeulemeester J; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Integrative Cancer Genomics Laboratory, Department of Oncology, KU Leuven, Leuven, Belgium.; VIB - KU Leuven Center for Cancer Biology, Leuven, Belgium.; Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Adusumilli PS; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tan KS; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Cheema W; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Sanchez-Vega F; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Jones DR; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Rekhtman N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Travis WD; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, UK.; Marafioti T; Department of Cellular Pathology, University College London Hospitals, London, UK.; Salgado R; Department of Pathology, ZAS Hospitals, Antwerp, Belgium.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Pathology Department, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK.; Nicholson AG; Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.; Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. Charles.Swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. Charles.Swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.Swanton@crick.ac.uk.; Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. m.jamal-hanjani@ucl.ac.uk.

Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Abbosh C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. c.abbosh@ucl.ac.uk.; Frankell AM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Harrison T; Invitae, San Francisco, CA, USA.; Kisistok J; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.; Garnett A; Invitae, San Francisco, CA, USA.; Johnson L; Invitae, San Francisco, CA, USA.; Veeriah S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Moreau M; Invitae, San Francisco, CA, USA.; Chesh A; Invitae, San Francisco, CA, USA.; Chaunzwa TL; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Weiss J; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Department of Radiology, Freiburg University Hospital, Freiburg, Germany.; Schroeder MR; Invitae, San Francisco, CA, USA.; Ward S; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Advanced Sequencing Facility, The Francis Crick Institute, London, UK.; Grigoriadis K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Shahpurwalla A; Invitae, San Francisco, CA, USA.; Litchfield K; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Tumour Immunogenomics and Immunosurveillance Laboratory, University College London Cancer Institute, London, UK.; Puttick C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Biswas D; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Bill Lyons Informatics Centre, University College London Cancer Institute, London, UK.; Karasaki T; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK.; Black JRM; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Martínez-Ruiz C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; Bakir MA; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.; 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Charles.Swanton@crick.ac.uk.; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. Charles.Swanton@crick.ac.uk.; Department of Oncology, University College London Hospitals, London, UK. Charles.Swanton@crick.ac.uk.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE