학술논문
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'학술논문'
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Academic Journal
한국축산학회지 / Journal of Animal Science and Technology. Sep 01, 2025 67(5):989
Academic Journal
Gorbokon, Natalia; Teljuk, Katharina; Reiswich, Viktor; Lutz, Florian; Rico, Sebastian Dwertmann; Lühr, Clara; Bernreuther, Christian; Al Bunni, Yaryna Klos; Völkel, Cosima; Plage, Henning; Lennartz, Maximilian; Fisch, Margit; Minner, Sarah; Simon, Ronald; Sauter, Guido; Zecha, Henrik; Steurer, Stefan; Schlomm, Thorsten; Vlajnic, Tatjana; Bubendorf, Lukas; Rink, Michael; Kluth, Martina; Viehweger, Florian; Freytag, Morton
Scientific Reports. 15(1)
Academic Journal
Dagogo-Jack, Ibiayi ; Mitchell, Owen ; Codd, Elizabeth ; Li, Annie ; Mitchell, Dawn ; Flynn, Samantha E. ; Sivamanoharan, Nanna ; Reeves, Patrick ; Poznansky, Mark C. ; Valiev, Ivan ; Kosmin, Artem ; Yeap, Beow Y. ; Hambelton, Grace ; Iafrate, Anthony John ; Lennerz, Jochen K. ; Hung, Yin P. ; Kindler, Hedy
In Journal of Thoracic Oncology November 2025 20(11):1615-1625
Academic Journal
Report
PRIMROSE: A Modular Phase I/IIa, Multi-centre, Dose Escalation, and Expansion Study of AZD3470, a MTA Cooperative PRMT5 Inhibitor, as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumors That Are MTAP Deficient
Report
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG908 in Patients With MTAP -deleted Advanced or Metastatic Solid Tumors
Briggs KJ, Cottrell KM, Tonini MR, Tsai A, Zhang M, Whittington DA, Zhang W, Lombardo SA, Yoda S, Wilker EW, Meier SR, Yu Y, Teng T, Huang A, Maxwell JP. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment ofMTAP -deleted cancers. Transl Oncol. 2025 Feb;52:102264. doi: 10.1016/j.tranon.2024.102264. Epub 2025 Jan 4.
Briggs KJ, Cottrell KM, Tonini MR, Tsai A, Zhang M, Whittington DA, Zhang W, Lombardo SA, Yoda S, Wilker EW, Meier SR, Yu Y, Teng T, Huang A, Maxwell JP. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of
Report
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG462 as a Single Agent and in Combination in Patients With MTAP -deleted Advanced or Metastatic Solid Tumors
Report
A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics and Preliminary Clinical Activity of BAY 3713372, a Novel 2nd Generation PRMT5 Inhibitor, in Participants With MTAP -deleted Solid Tumors.
Report
A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Antitumor Activity of TNG456 Monotherapy and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
Report
A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 193 in Combination With Other Therapies in Subjects With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous MTAP -deletion
Report
A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP -deletion (Master Protocol)
Report
A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma
Academic Journal
Chang WH; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Comprehensive Cancer Center, University of California, Davis, Sacramento, CA, United States.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Zhang J; Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Comprehensive Cancer Center, University of California, Davis, Sacramento, CA, United States.; Hong QS; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Chen CH; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA, United States.; Comprehensive Cancer Center, University of California, Davis, Sacramento, CA, United States.
Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Academic Journal
Salzano, Serena ; Caltabiano, Rosario ; Magro, Gaetano ; D'Amati, Antonio ; Pizzimenti, Cristina ; Maugeri, Andrea ; Agodi, Antonella ; Barbagallo, Giuseppe ; Certo, Francesco ; Fiorentino, Francesco ; Tuccari, Giovanni ; Martini, Maurizio ; Ieni, Antonio ; Barresi, Valeria ; Broggi, Giuseppe
In Annals of Diagnostic Pathology December 2025 79
Report
A Multicenter, Randomized, Open-label, Phase 2 Study Evaluating the Safety and Efficacy of BMS-986504 Monotherapy in Participants With Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion After Progression on Prior Therapies
Report
A Randomized, Phase 2/3 Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion
Report
A Randomized Phase 2/3 Study of BMS-986504 in Combination With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Report
A Phase 1 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion
Report
An Open Label, Phase 1, Treatment Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of IDE397 (MAT2A Inhibitor) In Adult Participants With Advanced Solid Tumors
Report
A Phase 1/2, Open-label, Multicenter Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Antineoplastic Activity of S095035 (MAT2A Inhibitor) as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Homozygous Deletion of MTAP
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