학술논문

발행년
-
(예 : 2010-2015)
'학술논문' 에서 검색결과 75건 | 목록 1~10
Academic Journal
PEDIATRICS; OCT 2023, 152 4, pe2023061501 6p.
Periodical
Journal of the American Geriatrics Society. April, 2022, Vol. 70 Issue 4, p1292, 5 p.
Skeletal Effects of Sleeve Gastrectomy in AContext: Vertical sleeve gastrectomy (VSG) is an increasingly common tool to achieve weight loss and improve metabolic health in adolescents and young adults with obesity, although it may adversely affect bone health. Objective: This work aimed to evaluate the effect of VSG on bone health in youth. Methods: An observational 2-year study was conducted at a tertiary care center of 66 patients aged 13 to 24 years with moderate-to-severe obesity meeting criteria for VSG. The patients underwent VSG (n= 30) or nonsurgical (n=36) management per the decision of patient and clinical team. Main outcome measures included dual-energy x-ray absorptiometry (DXA) and high-resolution peripheral quantitative computed tomography (HRpQCT) measures of bone mineral density (BMD), geometry, and microarchitecture. Results: VSG patients achieved 25.3±2.0% weight loss at 2 years (P<.001) while control subjects gained 4.0±2.0% (P= .026). Total hip BMD declined 8.5±1.0% following VSG compared with 0.1±1.0% gain in controls (P< .001), with similar results at the femoral neck (P<.001). Total volumetric BMD (vBMD) decreased both at the distal radius and tibia following VSG (P<.001) driven primarily by trabecular vBMD loss (P< .001). Two-year changes in cortical vBMD did not differ between groups, though cortical porosity decreased following VSG both at the radius and tibia (P=.048 and P< .001). Cortical thickness increased in controls but not in VSG (P=.022 and P= .002 for between-group comparisons at the radius and tibia, respectively). Following VSG, estimated failure load decreased at the radius and did not demonstrate the physiologic increases at the tibia observed in controls. Conclusion: VSG leads to progressive changes in bone health over 2 years, and may lead to increased skeletal fragility in adolescents and young adults.dolescents and Young Adults: A 2-Year Longitudinal Study.
Academic Journal
Journal of Clinical Endocrinology & Metabolism; Apr2023, Vol. 108 Issue 4, p847-857, 11p
검색 결과 제한하기
제한된 항목
[AR] Stanford, Fatima C.
발행연도 제한
-
학술DB(Database Provider)
저널명(출판물, Title)
출판사(Publisher)
자료유형(Source Type)
주제어
언어