학술논문

Tether extraction from endothelial cells with the micropipette aspiration technique.
Document Type
Theses
Source
Dissertation Abstracts International; Dissertation Abstract International; 66-10B.
Subject
Engineering, Biomedical
Biology, Cell
Biophysics, General
Language
English
Abstract
Summary: Additionally, the effects of cholesterol depletion and enrichment on tether extraction from endothelial cells and neutrophils are quantified. The importance of cholesterol in regulating membrane fluidity and adhesion to the underlying cytoskeleton is elucidated. Overall, this dissertation substantially improves the current understanding of the regulation of leukocyte rolling by introducing the endothelial cell tether into the broader picture.