학술논문
Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial
Document Type
Article
Author
Turkova, Anna; White, Ellen; Kekitiinwa, Adeodata R; Mumbiro, Vivian; Kaudha, Elizabeth; Liberty, Afaaf; Ahimbisibwe, Grace Miriam; Moloantoa, Tumelo; Srirompotong, Ussanee; Mosia, Nozibusiso Rejoice; Puthanakit, Thanyawee; Kobbe, Robin; Fortuny, Clàudia; Kataike, Hajira; Bbuye, Dickson; Na-Rajsima, Sathaporn; Coelho, Alexandra; Lugemwa, Abbas; Bwakura-Dangarembizi, Mutsa F; Klein, Nigel; Mujuru, Hilda A; Kityo, Cissy; Cotton, Mark F; Ferrand, Rashida A; Giaquinto, Carlo; Rojo, Pablo; Violari, Avy; Gibb, Diana M; Ford, Deborah; Mehar (nee Abdulla), Amina Farhana; Abraham, Pattamukkil; Abrams, Elaine; Acero, Judith; Agaba, Gerald Muzorah; Ahimbisibwe, Grace; Ainebyoona, Barbara; Akobye, Winnie; Akhalwaya, Yasmeen; Akoojee, Nazim; Ali, Shabinah S.; Amuge, Pauline; Andrea, Catherine; Muñoz Fernandez, Maria Angeles; Ankunda, Rogers; Rutebarika, Diana Antonia; Anugulruengkitt, Suvaporn; Apollo, Tsitsi; Archary, Moherndran; Arendze, Ronelle; Ategeka, Juliet; Atim, Eunice; Atwine, Lorna; Babiker, Abdel; Babirye, Sarah; Babu, Enock; Bagirigomwa, Edward; Baita, Angella; Balamusani, David; Baliram, Patsy; Baliruno, David; Ball, Colin; Balwa, Henry; Bamford, Alasdair; Bandi, Srini; Barker, Dominique; Barlow-Mosha, Linda; Bbuye, Dickson; Begum, Shazia; Behuhuma, Osee; Bernays, Sarah; Besigye, Rogers; Bester, Maria; Bhiri, Joyline; Bilardi, Davide; Bird, Kristien; Bollen, Pauline; Borg, Chiara; Borges Da Silva, Anne-Marie; Brown, Jackie; Bruno, Elena; Bunupuradah, Torsak; Burger, David; Buthelezi, Nomzamo; Bwakura-Dangarembizi, Mutsa; Byaruhanga, Africanus; Calvert, Joanna; Casey, Petronelle; Cassim, Haseena; Cebekhulu, Sphiwee; Chailert, Sanuphong; Chalermpantmetagul, Suwalai; Chamjamrat, Wanna; Chan, Man; Chandiwana, Precious; Chankun, Thannapat; Chanthaburanun, Sararut; Chanto, Nuttawut; Chidziva, Ennie; Chikowore, Minenhle; Chimanzi, Joy; Chinwong, Dujrudee; Chitongo, Stuart; Chitsamatanga, Moses; Choga, Joshua; Chutima, Duangrat; Clayden, Polly; Coelho, Alexandra; Colbers, Angela; Compagnucci, Alexandra; Constança Mendes, Ana; Conway, Magda; Cotton, Mark F; Crawley, Jane; Cressey, Tim R; Crisp, Jacky; Matos, Ana Cristina; Dadan, Sumaya; Daglish, Jacqui; Danaviah, Siva; Daniel, Tseleng; De Rossi, Anita; Denjanta, Sukanda; Dobbels, Els; Dowie, Maria; Dube, Prosper; Dube, Benedictor; Dudakia, Nimisha; Elwana, Alice; Epalza, Cristina; Eram, David; Erasmus, Juan; Erim, Peter; Escosa Garcia, Luis; Essack, Zaakirah; Estepa, Carolina; Etima, Monica; Fernandes, Alexandre; Fernandez, Maite; Fitzgerald, Felicity; Flynn, Jacquie; Ford, Deborah; Fortuny Guasch, Claudia; Foster, Caroline; Fourie, George; Fourie, Yolandie; Foxall, Sophie; Frank, Derusha; Gandhi, Kate; Garcia, India; Gartner, Kathleen; Gasa, Joshua; Gasa, Gugu; Giaquinto, Carlo; Gibb, Diana M; Gomez Rico, Coral; Gomez-Pena, Daniel; Gondo, Secrecy; Goodman, Anna; Gorreti Nakalema, Maria; Gozhora, Winnie; Greetanukroh, Pisut; Gregorio Maranon, Biobanco; Grossele, Tiziana; Gwande, Shamiso; Gwaze, Tapiwa; Gwenzi, Tsitsi; Hakim, James; Hakiza, Emmanuel; Kaka, Abdul Hamid; Harley, Ashley; Isaacs, Mornay; Isabirye, Richard; Ishemunyoro, Wilber; Jacobs, Tom; Jafta, Lungile; Jamil, Nasir; Janse van Rensburg, Anita Janse; Jeaven, Vinesh; Mellado Peña, Maria José; Jourdain, Gonzague; Juliet, Katabalwa; Jumpimai, Thidarat; Junkaew, Raungwit; Jupimai, Thidarat; Kaahwa, Winfred; Kabasonga, Mildred; Kaboggoza, Olivia; Kadhuba, Rose Jacqueline; Kaewbundit, Ampika; Kaewmamueng, Kanyanee; Kafufu, Bosco; Kakayi, Brenda; Kamboua, Phakamas; Kanjanavanit, Suparat; Kasangaki, Gladys; Kasipong, Naruporn; Kasozi, Miriam; Kataike, Hajira; Katemba, Chrispus; Kaudha, Elizabeth; Kekane, Nkata; Kekitiinwa, Adeodata R; Keminyeto, Edridah; Khamduang, Woottichai; Khamjakkaew, Warunee; Khamkon, Jiraporn; Khannak, Sasipass; Khatngam, Orapin; Khayanchoomnoom, Tassawan; Khumalo, Busi; Khunene, Mirriam; Khusuwan, Suwimon; Kibalama, Phionah; Kibenge, Robinah; Kirabira, Anthony; Kityo, Cissy M; Kiyimba, Lameck; Klein, Nigel; Klinprung, Soraya; Kobbe, Robin; Kobusingye, Olivia; Kobusungye, Josephine; Kongponoi, Areerat; Königs, Christoph; Koole, Olivier; Kouakam, Christelle; Krueduangkam, Nitinart; Kruenual, Namthip; Kunjaroenrut, Nuananong; Kyambadde, Raymonds; Kyobutungi, Priscilla; Kyomuhendo, Flavia; Kyomukama, Erinah; Lakha, Reshma; Langa, Cleopatra; Laomanit, Laddawan; Lebotsa, Emily; Leenasirimakul, Prattana; Lekku, Lawrence; Lensen, Sarah; Leroy, Valériane; Li, Jin; Liberty, Afaaf; Limplertjareanwanich, Juthamas; Little, Emma; Lugemwa, Abbas; Lutalo, Ezra; Jimenez, Jose Luis; Lyall, Hermione; MacDonald, Candice; Machache, Gladness; Madlala, Penelope; Madonsela, Tryphina; Maduna, Nomfundo; Maena, Joel; Mahanontharit, Apicha; Makanga, Collin; Makola, Candice; Makumbi, Shafic; Malgraaf, Lucille; Mamiane, Angelous; Mantkowski, Felicia; Mapfumo, Wendy; Marques, Laura; Mugagga, Agnes Mary; Maseko, Lindiwe; Masienyane, Tshepiso; Mathiba, Ruth; Matimba, Farai; Mawlana, Sajeeda; Mayanja, Emmanuel; Mayat, Fatima; Mbabazi, Ritah; Mbadaliga, Nokuthula; Mbasani, Faith; McClaughlin, Kathleen; McIlleron, Helen; Meethaisong, Watchara; Mendez Garcia, Patricia; Miwanda, Annet; Miranda, Carlota; Mkhize, Siphiwe; Mmolawa, Kgosimang; Mngqibisa, Rosie; Mohamed, Fatima; Moloantoa, Tumelo; Monametsi, Maletsatsi; Montero, Samuel; Moore, Cecilia L; Mosia, Rejoice; Moyo, Columbus; Mthethwa, Mumsy; Mudzingwa, Shepherd; Mudzviti, Tawona; Mujuru, Hilda; Mujyambere, Emmanuel; Mukanganiki, Trust; Mukisa Williams, Cynthia; Mulder, Mark; Mulima, Disan; Mulindwa, Alice; Mumbiro, Vivian; Mupambireyi, Zivai; Murciano Cabeza, Alba; Murungi, Herbert; Murungu, Dorothy; Musarurwa, Sandra; Musiime, Victor; Musiime, Alex V; Musisi, Maria; Musoke, Philippa; Musoke Nakirya, Barbara; Musoro, Godfrey; Musumba, Sharif; Mustafa, Sobia; Mutsai, Shirley; Mwesigwa Rubondo, Phyllis; Naabalamba, Mariam; Nagawa, Immaculate; Naidoo, Allemah; Nakabuye, Shamim; Nakabuye, Sarah; Nakalanzi, Sarah; Nalubwama, Justine; Nalugo, Annet; Nalusiba, Stella; Namajja, Clementine; Namanda, Sylvia; Namayanja, Paula; Nambi, Esther; Namuddu, Rachael Kikabi; Namukwaya, Stella; Namuli, Florence; Namusanje, Josephine; Namwanje, Rosemary; Nanan-kanjee, Anusha; Nanduudu, Annet; Nankunda, Charity; Baddokwaya, Joanita Nankya; Nannungi, Maria; Nansamba, Winnie; Nanthapisal, Kesdao; Nanyonjo, Juliet; Na-Rajsima, Sathaporn; Nasaazi, Claire; Nascimento, Helena; Nastouli, Eleni; Songtaweesin, Wipaporn Natalie; Nathoo, Kusum; Natuhurira, Ian; Nazzinda, Rashidah; Ncgaba, Thabisa; Ndigendawani, Milly; Ndlovu, Makhosonke; Nentsa, Georgina; Ngampiyaskul, Chaiwat; Ngcobo, Ntombenhle; Ngo Giang Huong, Nicole; Ngwaru, Pia; Nhema, Ruth; Ninsiima, Emily; Ninsiima, Gloria; Nkalo Phiri, Misheck; Noguera Julian, Antoni; Nolan, Monica; Noppakaorattanamanee, Thornthun; Nsibuka Kisekka, Muzamil; Nsirim, Eniola; Nundlal, Rashina; Nunes, Rosita; Nyantsa, Lungile; Nyati, Mandisa; O'Riordan, Sean; Ocitti Labeja, Paul; Odoch, Denis; Oguntimehin, Rachel; Ojok, Martin; Onen, Geoffrey; Orange, Wilma; Ounchanum, Pradthana; Ouma, Benson; Padrao, Andreia; Pako, Deborah; Parker, Anna; Pasko-Szcech, Malgorzata; Patel, Reena; Peongjakta, Rukchanok; Petpranee, Turian; Phillips, Tasmin; Philps, Jackie; Picault, Laura; Pieterse, Sonja; Pinheiro, Helena; Pongprapass, Supawadee; Pozniak, Anton; Prendergast, Andrew; Prieto Tato, Luis; Puangmalai, Patcharee; Puthanakit, Thanyawee; Rakgokong, Modiehi; Ramos, Helena; Ramsagar, Nastassja; Rau, Cornelius; Riault, Yoann; Rojo Conejo, Pablo; Clark, Basiimwa Roy; Rubanga, Eddie; Rubinga, Baker; Ruklao, Chutima; Runarassamee, Pattira; Rutebarika, Diana Antonia; Saenjum, Chalermpong; Saewtrakool, Chayakorn; Saidi, Yacine; Sainz Costa, Talia; Saisaengjan, Chutima; Sakwa, Rebecca; Sarfati, Tatiana; Sbisi, Noshalaza; Scheppers, Dihedile; Schultze-Strasser, Stephan; Schulze-Sturm, Ulf; Scott, Karen; Seeley, Janet; Serunjogi, Robert; Sewnarain, Leora; Shakeshaft, Clare; Sidhoo, Subashinie; Shibemba, Mercy; Shingadia, Delane; Singh, Sheleika; Sirirungsi, Wasna; Sithebe, Sibongile; Smit, Theresa; Smith, Kurt; Smuts, Marlize; Spyer, Moira; Sripaoraya, Worathip; Srirompotong, Ussanee; Srisuk, Warunee; Ssenyonga, Mark; Sudsaard, Patamawadee; Sukrakanchana, Praornsuda; Tearsansern, Pathanee; Teixeira, Carla; Than-in-at, Kanchana; Thapwai, Thitiwat; Thaweesombat, Yupawan; Thewsoongnoen, Jutarat; Thiébaut, Rodolphe; Thomason, Margaret; Thrasyvoulou, Laura; Thungkham, Khanungnit; Tikabibamu, Judith; Tinago, Gloria; Trairat, Ketmookda; Tudor-Williams, Gareth; Tukamushaba, Mercy; Tukwasibwe, Deogratiuos; Tumusiime, Julius; Tuna, Joana; Turkova, Anna; Turner, Rebecca; Udomvised, Arttasid; Vadee, Aasia; Van Huyssteen, Hesti; Van Looy, Nadine; Variava, Ebrahim; Vaughan-Gordon, Yvonne; Vecchia, Giulio; Violari, Avy; Vowden, Richard; Waalewijn, Hylke; Wampamba, Rebecca; Welch, Steve; Weller, Ian; Weza, Sibusisiwe; White, Ellen; White, Ian; Widuch, Kaja; Wilkes, Helen; Wimonklang, Sookpanee; Wynne, Ben; Yingyong, Pacharaporn; Nakawungu, Zaam Zinda; Zuidewind, Peter
Source
The Lancet Child & Adolescent Health; October 2023, Vol. 7 Issue: 10 p718-727, 10p
Subject
Language
ISSN
23524642; 23524650
Abstract
Cohort studies in adults with HIV showed that dolutegravir was associated with neuropsychiatric adverse events and sleep problems, yet data are scarce in children and adolescents. We aimed to evaluate neuropsychiatric manifestations in children and adolescents treated with dolutegravir-based treatment versus alternative antiretroviral therapy.