학술논문
Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials
Document Type
Article
Author
Majoie, Charles B; Cavalcante, Fabiano; Gralla, Jan; Yang, Pengfei; Kaesmacher, Johannes; Treurniet, Kilian M; Kappelhof, Manon; Yan, Bernard; Suzuki, Kentaro; Zhang, Yongwei; Li, Fengli; Morimoto, Masafumi; Zhang, Lei; Miao, Zhongrong; Rinkel, Leon A; Huang, Jiacheng; Otsuka, Toshiaki; Wang, Shouchun; Davis, Stephen; Cognard, Christophe; Hong, Bo; Coutinho, Jonathan M; Song, Jiaxing; Chen, Wenhuo; Emmer, Bart J; Eker, Omer; Zhang, Liyong; Dobrocky, Tomas; Nguyen, Huy-Thang; Bush, Steven; Peng, Ya; LeCouffe, Natalie E; Takeuchi, Masataka; Han, Hongxing; Matsumaru, Yuji; Strbian, Daniel; Lingsma, Hester F; Nieboer, Daan; Yang, Qingwu; Meinel, Thomas; Mitchell, Peter; Kimura, Kazumi; Zi, Wenjie; Nogueira, Raul G; Liu, Jianmin; Roos, Yvo B; Fischer, Urs; Zi, Wenjie; Nogueira, Raul; Yang, Qingwu; Liu, Jianmin; Yang, Pengfei; Zhang, Yongwei; Yan, Bernard; Mitchell, Peter; Miao, Zhong Rong; Majoie, Charles B.; Roos, Yvo B.; Suzuki, Kentaro; Kimura, Kazumi; Matsumaru, Yuji; Fischer, Urs; Gralla, Jan; Cavalcante, Fabiano W.; Kappelhof, Manon; Treurniet, Kilian M.; Kaesmacher, Johannes; Zhang, Lei; Bush, Steven; Nieboer, Daan; Lingsma, Hester F.; Rothwell, Peter; Saver, Jeffrey; Fiehler, Jens; Li, Fengli; Huang, Jiacheng; Song, Jiaxing; Hong, Bo; Chen, Wenhuo; Peng, Ya; Han, Hongxing; Zhang, Liyong; Li, Zifu; Xing, Pengfei; Shen, Hongjian; Zhang, Ping; Zhang, Xiaoxi; Davis, Stephen; Nguyen, Huy-Thang; Donnan, Geoffrey; Huo, Xiaochuan; Nan, Guangxian; Bivard, Andrew; Ma, Henry; Vu, Dang Lu; Campbell, Bruce; Rinkel, Leon A.; Emmer, Bart J.; Coutinho, Jonathan M.; LeCouffe, Natalie E.; Dippel, Diederik W.; van der Lugt, Aad; van Zwam, Wim H.; van Oostenbrugge, Robert J.; Uyttenboogaart, Maarten; Costalat, Vincent; Lycklama, Geert; Hofmeijer, Jeannette; van Norden, Anouk; Otsuka, Toshiaki; Takeuchi, Masataka; Morimoto, Masafumi; Kanazawa, Ryuzaburo; Takayama, Yohei; Kamiya, Yuki; Shigeta, Keigo; Okubo, Seiji; Hayakawa, Mikito; Strbian, Daniel; Eker, Omer; Cognard, Christophe; Meinel, Thomas; Dobrocky, Tomas; Jung, Simon; Piechowiak, Eike; Marnat, Gaultier; Sibon, Igor; Bourcier, Romain; de Gaalon, Solene; Papagiannaki, Chrysanthi; Lefebvre, Margaux
Source
The Lancet; September 2023, Vol. 402 Issue: 10406 p965-974, 10p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Intravenous thrombolysis is recommended before endovascular treatment, but its value has been questioned in patients who are admitted directly to centres capable of endovascular treatment. Existing randomised controlled trials have indicated non-inferiority of endovascular treatment alone or have been statistically inconclusive. We formed the Improving Reperfusion Strategies in Acute Ischaemic Stroke collaboration to assess non-inferiority of endovascular treatment alone versus intravenous thrombolysis plus endovascular treatment.