학술논문
Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors
Document Type
Article
Author
Source
Blood; 20230101, Issue: Preprints
Subject
Language
ISSN
00064971; 15280020
Abstract
1)The first full-length structures of human arachidonate 12S-Lipoxygenase (12-LOX) reveal mechanisms of oligomeric and conformational states2)The structures uncover natural inhibitor of 12S-Lipoxygenase (12-lox) and reveal a binding site of inhibitor ML355