학술논문
The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
Document Type
Article
Author
Ma, Lu; Hu, Xin; Song, Lili; Chen, Xiaoying; Ouyang, Menglu; Billot, Laurent; Li, Qiang; Malavera, Alejandra; Li, Xi; Muñoz-Venturelli, Paula; de Silva, Asita; Thang, Nguyen Huy; Wahab, Kolawole W; Pandian, Jeyaraj D; Wasay, Mohammad; Pontes-Neto, Octavio M; Abanto, Carlos; Arauz, Antonio; Shi, Haiping; Tang, Guanghai; Zhu, Sheng; She, Xiaochun; Liu, Leibo; Sakamoto, Yuki; You, Shoujiang; Han, Qiao; Crutzen, Bernard; Cheung, Emily; Li, Yunke; Wang, Xia; Chen, Chen; Liu, Feifeng; Zhao, Yang; Li, Hao; Liu, Yi; Jiang, Yan; Chen, Lei; Wu, Bo; Liu, Ming; Xu, Jianguo; You, Chao; Anderson, Craig S; Robinson, Thompson; Miranda, J. Jaime; Anderson, Craig S.; You, Chao; Song, Lili; Parry-Jones, Adrian; Sprigg, Nikola; Durrans, Sophie; Harris, Caroline; Bamford, Ann; Smith, Olivia; Herbert, Robert; Chen, Christopher; Whiteley, William; Hu, Rong; Billot, Laurent; Li, Qiang; Mysore, Jayanthi; Hu, Xin; Zhang, Yao; Liu, Feifeng; Sakamoto, Yuki; You, Shoujiang; Han, Qiao; Crutzen, Bernard; Li, Yunke; Cheung, Emily; Jan, Stephen; Liu, Hueiming; Ouyang, Menglu; Sun, Lingli; Chu, Honglin; Anjum, Anila; Gonzalez Mc Cawley, Francisca; Del Rio, Alejandra; Rimoli, Bruna; Cerantola, Rodrigo; Jeevarajah, Thanushanthan; Kannangara, Madhushani; Joseph, Andrene; Nanayakkara, Chamath; Chen, Xiaoying; Malavera, Alejandra; Zhang, Chunmiao; Yang, Zhao; Li, Brook; Meng, Zhuo; Ouyang, Menglu; Liu, Leibo; Ning, Yi; Dong, Le; Armenis, Manuela; Lim, Joyce; Monaghan, Helen; Ma, Lu; Hu, Xin; Li, Xi; Luo, Rui; Cheng, Guojuan; Dong, Yilin; Liu, Ziqin; Wang, Shuihong; Zhang, Ying; Cheng, Jipeng; Shi, Hui; Li, Wenjing; Mou, Langming; Yi, Ping; Chen, Chen; Chen, Xue; Weerawardena, Shalomi; Ellawala, Poornima; Ranasinghe, Enalee; Rodrigo, Chrishmi; Wahab, Kolawala; Adeniyi, Sunday; Pandian, Jeyaraj; Khanna, Megha; Muñoz Venturelli, Paula; González, Francisca; Urrutia Goldsack, Francisca; Wasay, Mohammad; Begum, Dilshad; Anjum, Anila; Pontes-Neto, Octavio; Camilo, Millene; Dias, Francisco; Vincenzi, Octavio; Cerantola, Rodrigo; Moro, Carla; Santos, Renata; Texeira, Nara; Longo, Alexandre; Liberato, Rafaela; Martins, Sheila; Pille, Arthur; Chwal, Bruna; Silva, Isabel; Titton, Natacha; Weiss, Gustavo; Mora, Daissy; Ouriques, Magda; Carbonera, Leonardo; Bazan, Rodrigo; Modolo, Gabriel; Winckler, Fernanda; Miranda, Luana; Souza, Juli; Rojo, Alexis; Uslar, Wilhelm; Medel, Lorena; Lopez, Javiera; Herrero, Diego; Lavados, Pablo; Vargas Latorre, Barbara; Conejan, Nathalie; Esparza, Tomas; Sotomayor, Patricio; Wenger, Denisse; Gigoux, Juan Pablo; Letelier, Aldo; Acevedo, Lilian; Moya, Vivianne; Figueroa, Cristian; Vallejos, Nicol; Conejan, Nathalie; Esparza, Tomas; Sotomayor, Patricio; Guerrero, Rodrigo; Velasquez, Mauricio; Vallejos, Jose; Pallauta, Kimerly; Santibanez, Tamara; Queirolo, Angelo; Lobos, Andrea; Jiang, Yongming; Li, Weimin; Huang, Wei; Luo, Ke; Liu, Gangying; Tang, Guanghai; Yang, Guang; Jiang, Hongtao; Zhang, Xu; Jing, Hongyan; Zhu, Sheng; Pu, Bo; Lv, Dong; Kang, Hui; Hu, Qiuping; She, Xiaochun; Jiang, Xiaoming; Chen, Yanli; Yang, Shenghua; He, Jianjun; Li, Zongping; Cheng, Gang; Huang, Hailin; Wang, Xiaoyi; Lin, Jianqiong; Chen, Minhui; Yang, Chenghao; Ding, Hao; Deng, Yunliang; Luo, Fei; Zhang, Rongjun; Wang, Xiaofeng; Zhang, Hongbing; Yang, Xiaoliang; Zhang, Yang; Yang, Chengyi; He, Yu; Liu, Feng; Wang, Rongjie; Zhang, Yuhui; Xin, Xiaodong; Feng, Bin; Hao, Wanru; Song, Chang; Guo, Yun; Jiang, Dehua; Chen, Jie; Tang, Changtong; Zhu, Hongliang; Li, Xin; Cui, Jin; Xu, Haidong; Li, Boyang; Tang, Fusheng; Li, Yuanbin; Gao, Min; Yang, Bo; Xu, Xuejun; Deng, Bing; Zheng, Yi; Ge, Yuanhong; Chen, Keyu; Liu, Yang; Li, Xinshen; Zhong, Tingting; Xu, Jianfeng; Zhang, Hai; Wang, Jiyue; Zhu, Jianxin; Sun, Hanyu; Yu, Fuhua; Zhang, Xueguang; You, Chao; Ma, Lu; Hu, Xin; Xu, Jianguo; Li, Xi; Zhang, Mingsen; Wang, Bin; Ma, Yiming; Jiang, Donglin; Zhou, Jun; Liu, Cong; Nie, Wenhong; Li, Mingguo; Tian, Tao; Li, Yong; He, Mingfang; Tu, Xiaolong; Wu, Zhengjun; Liu, Hong; Zhong, Dongsheng; Jiang, Rongcai; Sun, Jian; Tian, Ye; Wei, Yingsheng; An, Shuo; Wei, Pingbo; Luo, Le; Lin, Bin; Liu, Gang; Wen, Yan; Cai, Qiang; Chen, Qianxue; Lei, Pan; Li, Zhiyang; Zhang, Meifang; He, Jiaquan; Chen, Yan; Liu, Jun; Liu, Xinghai; Li, Junyan; Chen, Min; Wang, Jing; Zhou, Bingzhi; Ye, Baichun; Zhang, Jiancheng; Zhang, Manyuan; Pan, Xuming; Yu, Xiaoxiang; Xu, Jian; Xiao, Qingbao; Wang, Yuefei; Tao, Liang; Shi, Lin; Zheng, Niandong; You, Guoliang; Lei, Bo; Chen, Shu; Wu, Honggang; Hu, Jin; Zhao, Jianlan; Yu, Jian; Yuan, Qiang; Du, Zhuoying; Tang, Xielin; Li, Qianke; Liu, Shenghua; Yang, Feilong; Xiao, Kui; Luo, Chao; Wang, Guang; Che, Xudong; Teng, Zhipeng; Wan, Wenwu; Li, Jun; Liu, Yu; Fan, Mingbo; Zhang, Tao; Cai, Lun; Ma, Yuan; Ma, Zhifeng; Li, Bin; He, Linlin; Li, Jinghui; Zhang, Weibing; Zhang, Shuxin; Zhang, Hongzhen; Dai, Yingguang; Lei, Jun; Mao, Lei; Huang, Yiyang; Zhou, Zhi; Chen, Ping; Chen, Fang; Wei, Pan; Li, Tiangui; Chen, Honglin; Zeng, Mengfei; Mou, Kejie; Xue, Jun; Jiang, Yong; Tang, Xiaoping; Chen, Tao; Zhang, Yalan; Xu, Yanbing; Gu, Yuchen; Chen, Lei; Zhao, Yujun; Yang, Bin; Kuai, Peng; Wang, Xi; Yang, Yuwang; Hu, Xueling; Zhang, Huitian; Yang, Yintao; Wang, Weifeng; Zhang, Junyi; Cheng, Wei; Zhang, Xiaoxue; Ma, Xiaowen; He, Qin; Zhang, Li; Gao, Rong; Liu, Huixiang; Ye, Jingwei; Xu, Ping; Wu, Xin; Yuan, Yuan; Zou, Peng; Zhang, Zhen; Cheng, Jiyong; Zhou, Zhangming; Zeng, Yijun; Liang, Zhang; Du, Deming; Yu, Shui; Cao, Yongjun; You, Shoujiang; Xu, Jiaping; Huang, Zhichao; Chen, Dongqin; Xiao, Wenfeng; Zhu, Li; Yuan, Miao; Wang, Yuhai; Shi, Dongliang; Hu, Xu; Xiang, Dingchao; Shi, Like; Wang, Hongqin; Yang, Liu; Miao, Wang; Hu, Yiyi; Zhao, Yuchun; Hu, Xi; Liu, Yang; Zhou, Weiduo; Sun, Chao; Chen, Tao; Tang, Dong; Yao, Kun; You, Jin; Chen, Shishi; Yao, Jianmin; Li, Huanmei; Liu, Jinmei; Bai, Ailin; Yi, Yong; Deng, Qingshan; Luo, Peng; Wang, Han; Jiang, Jingcheng; Yang, Qingwei; He, Shunpo; Wang, Jun; Chen, Yu; He, Hua; Deng, Yuyang; Cao, Zhikai; Yi, Xuxia; Luo, Jinbiao; Luo, Shuang; Gong, Min; Liu, Li; Gao, Xuejun; Liu, Jia; Wu, Li'e; Zhang, Jia; Sun, Hongying; Li, Xinhui; Jia, Lu; Wu, Jianbing; Zhang, Jie; Zhang, Huajun; Du, Chunfu; Li, Shun; Yang, Xiaobin; He, Jie; Liao, Lei; Zhou, Gezhi; Dong, Wentao; Chen, Yunxiang; Lin, Xiaofeng; Shui, Xujian; Zhang, Peng; Zhao, Yuan; Yang, Hongli; Zhao, Wenbin; Zhang, Xiaoyi; Chen, Jincao; Wu, Qian; Dai, Xuan; Tang, Baogui; Wang, Yinjuan; Liu, Tao; Zhang, Haixia; Duan, Faliang; Luo, Ming; Jiao, Qingfang; Lei, Guoliang; Wang, Dong; Song, Chunwang; Tan, Haopeng; Ye, Feng; Qin, Xinghu; Liang, Xiaolong; Liu, Junling; Yang, Lang; Yang, Jie; Lin, Yapeng; Yang, Qian; Ma, Xuntai; Qi, Yinkuang; Pan, Baogen; Jiang, Caixia; Ye, Zhanying; Dong, Ce; Yue, Xiongfei; Yang, Xiaopeng; Maimaitiyiming, Tuoheti; Dong, Jun; Wu, Yonggang; Gao, Feng; Zhao, Deqiang; Zhang, Xinghai; Wang, PengJun; Jiang, Hongbo; Li, Jianping; Zhang, Wei; Chen, Jing; Tong, Haibo; Wang, Yonghong; Qiao, Kaipeng; Guo, Fuyou; Zhang, Mingchu; Hu, Yan; Feng, Mengzhao; Song, Dengpan; Zuo, Yi; Chen, Shangjun; Qian, Chao; Li, Baoming; Ma, Jingku; Zhang, Sunfu; Kong, Bin; Dong, Xingyu; Li, Qiang; Fang, Sheng; Lu, Bin; Li, Yang; Zhang, Zhen; Yang, Yongling; Yu, Hong; Sun, Huaiyu; Wang, Yue; Wang, Weimin; Li, Tong; Li, Shengli; Xu, Zhiming; Wang, Yongyi; Dong, Qiang; Tang, Yuping; Chu, Heling; Lu, Ying; Wang, Zhong; Sun, Xiaoou; Zhao, Jianhua; Yang, Shuaifeng; Qian, Xiying; Saroja, Aralikatte Onkarappa; Naik k, Ravishankar; Chindhi, Sandip; Pampaniya, Nakul; Amaresh, Kurubara; Iype, Thomas; R, Dileep; Rajan, Reeja; Panicker, Praveen; Das, Rupjyoti; Choudhury, Nupur; Gohain, Pankaja; Webster, Jemin; Pakma, Biyol; Sangi, Lalbiak; Sebastian, Ivy; Aggrawal, Gaurav; Raj, Komal; Rajoura, Deepankshi; Singh, Sulena; Aggrawal, Varun; Narang, Amit; Arauz, Antonio; Cano-Nigenda, Vanesa; López-Mena, Diego; Valdez-Ruvalcaba, Héctor; Toledo-Treviño, Roberto; Obiako, Reginald; Abubakar, Sani; Emeka, Oguike; Olayemi, Balogun; Lois, Melika; Philip, Ibinaiye; Comfort O, Olurishe; Okubadejo, Njideka; Agabi, Osigwe; Ojo, Oluwadamilola; Wahab, Kolawole; Bello, Abiodun; Ibukun, Oyinloye; Sanayaolu, Olufemi; Adeniyi, Sunday; Jimoh, Abdulraheem; Wasay, Mohammad; Begum, Dilshad; Anjum, Anila; Waheed, Shahid; Kamal, Dr.Ayeesha; Shoaib, Raja Farhat; Orooj, Fizza; Majid, Sadaf; Zehra, Taskeen; Khan, Abdus Salam; Shanker, Ravi; Syed, Nadir Ali; Ahmad, Nashwa; Abanto, Carlos; Valencia, Ana; Barrientos, Danny; Ramirez, Jorge; Calle, Pilar; Palliyeguruge, Dilum; Muthucumarana, Sumudu; Ratnayaka, Shiroma; Ganihiarachchi, Dilhara; Bandaranayake, Arundathi; Somaratne, S.D.B; Narayana, Saumya; Gallage, Sithara; Senanayake, Bimsara; Samarasiri, Udari; Luke, Dunya; Sivapathasundaram, Mythily; Sahadevan, Vithoosan; Rasmi, Amani; Deshaka, Yuran; Fernando, Nilukshi; Munasinghe, Aruna; Rathnapriya, Kapilanga; Nissanka, A.S; Karunathilake, Kanchana; Gayan, Isuru; Wijenayake, Kaminda; Gunasekara, Hasitha; Vidyarathne, Jagath; Keshavaraj, Ajantha; Janarthanan, Kanagasabapathy; Gerald Jeevathasan, Arhivalaky; Sivamainthan, Sivaram; John Priyanth, Mathyamuthan; John Priyanth, Abirami; Rajendiran, Thambippillai; Alwis, Sanjeewa; Gunasekare, Nushara; Liyanarachchi, Vasundara; Dissanayake, Athula; Uluwattage, Wimalasiri Mewa; Ratnayake, Gimhani; Rajinee, Charika; Jayawardana, Sakura; Peiris, Janaka; Wicramasinghe, Ranjith; Fernando, Chamila; Abbas, Jessie; Withanage, Nethmini; Bandara, Makaranda; Mai, Duy Ton; Nguyen, Van Chi; Dao, Viet Phuong; Vuong, Xuan Trung; Nguyen, Tien Dung; Dinh, Trung Hieu; Phan, Ha Quan; Bui, Quoc Viet; Phung, Dinh Tho; Pham, Quang Tho; Pham, Dinh Dai; Do, Duc Thuan; Dang, Phuc Duc; Dang, Minh Duc; Nguyen, Dang Hai; Nguyen, Thi Phuong Nga; Nguyen, Quoc Huy; Pham, Quoc Dai; Chau, Quoc Vinh; Tai, Vinh Thy Van; Le, Tran Vinh; Le, Cong Tri; Tran, Ha Mai Khuong; Nguyen, Huu Khanh; Ngyen, Hoang Minh Thao; Vo, Duc Chien; Nguyen, Thai My Phuong; Tran, Trung Thanh; Vo, Thi Hanh Vi; Cao, Hao Nhien; Nguyen, Ba Thang; Le, Thi Ngoc Suong; La, Thien Duc; Pham, Chi Duc; Thai, Huy
Source
The Lancet; July 2023, Vol. 402 Issue: 10395 p27-40, 14p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Early control of elevated blood pressure is the most promising treatment for acute intracerebral haemorrhage. We aimed to establish whether implementing a goal-directed care bundle incorporating protocols for early intensive blood pressure lowering and management algorithms for hyperglycaemia, pyrexia, and abnormal anticoagulation, implemented in a hospital setting, could improve outcomes for patients with acute spontaneous intracerebral haemorrhage.