학술논문
Sickle cell anaemia and severe Plasmodium falciparummalaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT)
Document Type
Article
Author
Source
The Lancet Child & Adolescent Health; September 2022, Vol. 6 Issue: 9 p606-613, 8p
Subject
Language
ISSN
23524642; 23524650
Abstract
Sickle cell anaemia (SCA) has historically been associated with high levels of childhood mortality in Africa. Although malaria has a major contribution to this mortality, to date, the clinical pathology of malaria among children with SCA has been poorly described. We aimed to explore the relationship between SCA and Plasmodium falciparummalaria in further detail by investigating the burden and severity of malaria infections among children recruited with severe anaemia to the TRACT trial of blood transfusion in Africa.