학술논문
Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial
Document Type
Article
Author
Thompson, George R; Soriano, Alex; Cornely, Oliver A; Kullberg, Bart Jan; Kollef, Marin; Vazquez, Jose; Honore, Patrick M; Bassetti, Matteo; Pullman, John; Chayakulkeeree, Methee; Poromanski, Ivan; Dignani, Cecilia; Das, Anita F; Sandison, Taylor; Pappas, Peter G; Akova, Murat; AlAgha, Rawan; Alangaden, George; Albrecht, Svenja J; Alexander, Barbara; Al-Obaidi, Mohanad; Ambasch, German; Armestar Rodriguez, Fernando; Azap, Alpay; Baffoe-Bonnie, Anthony; Belkhir, Leila; Ben-Ami, Ronen; Boutoille, David; Cascio, Antonio; Chai, Louis YA; Chaiwarith, Romanee; Chayakulkeeree, Methee; Chen, Sharon; Chen, Yee-Chun; Chen, Yen-Hsu; Choi, Jun Yong; Choi, Young Hwa; Chotiprasitsakul, Darunee; Chung, Jin Won; Danion, François; Denis, Blandine; Diaz Santos, Emilio; Dictar, Miguel O; Diltoer, Marc; Dupont, Herve; Feng, Sizhou; Ferre Colomer, Maria Angeles; Ferrer, Ricard; Forel, Jean-Marie Fernand Roger; Fortún-Abete, Jesús; Garcia-Diaz, Julia; Girardis, Massimo; He, Fang; Hites, Maya; Ho, Mao-Wang; Honore, Patrick; Horcajada Gallego, Juan Pablo; Huang, Haihui; Huang, Po-Yen; Huang, Yong; Hussein, Osamah; Intalapaporn, Poj; Jaruratanasirikul, Sutep; Jauregui-Peredo, Luis; Johnson, Misty; Jung, Dong Sik; Jutivorakool, Kamonwan; Kern, Winfried V; Kett, Daniel H; Khawcharoenporn, Thana; Kim, Young Keun; Koehler, Philipp; Kotanidou, Anastasia; Lachiewicz, Anne; Lin, Qinhan; Lopez Cortes, Luis Eduardo; Luo, Hong; Luzzati, Roberto; Maor, Yasmin; McCarty, Todd; Merelli, Maria; Merino Amador, Paloma; Midturi, John; Migliorino, Guglielmo Marco; Mira, Jean-Paul; Mootsikapun, Piroon; Morrissey, Orla; Munoz Garcia de Paredes, Patricia; Mussini, Cristina; Mylonakis, Eleftherios; Nseir, Saadalla; Nseir, William; Odabasi, Zekaver; Papastamopoulos, Vasileios; Paterson, David; Patterson, Thomas F; Peck, Kyong Ran; Peng, Zhiyong; Permpalung, Nitipong; Plantefeve, Gaetan J; Poromanski, Ivan G; Powell, Debra; Psichogiou, Mina; Puah, Ser Hon; Pullman, John; Rahav, Galia; Martinez, Antonio Ramos; Ramos Ramos, Juan Carlos; Raz-Pasteur, Ayelet; Restrepo Castro, Carlos A; Riera, Fernando; Roblot, France; Rodriguez Alvarez, Regino Jose; Rogers, Benjamin; Roilides, Emmanuel; Sanchez Vallejo, Gregorio; Sganga, Gabriele; Sipsas, Nikolaos; Slavin, Monica; Soriano, Alex; Spec, Andrej; Strahilevitz, Jacob; Tancheva, Dora M; Tao, Zhen; Teschner, Daniel; Thompson, George R; Van Wijngaerden, Eric; Vazquez, Jose; Vergidis, Paschalis; Viale, Pierluigi; Wang, Fu-Der; Wang, Shifu; Weber, Gabriel; Weng, Jianyu; Xu, Jinfu; Yao, Li; Yavuz, Serap; Yilmaz, Mesut; Young, Jo-Anne; Zarate, Abel H; Zeng, Jun; Zhang, Yong
Source
The Lancet; January 2023, Vol. 401 Issue: 10370 p49-59, 11p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Rezafungin is a next-generation, once-a-week echinocandin in development for the treatment of candidaemia and invasive candidiasis and for the prevention of invasive fungal disease caused by Candida, Aspergillus, and Pneumocystisspp after blood and marrow transplantation. We aimed to compare the efficacy and safety of intravenous rezafungin versus intravenous caspofungin in patients with candidaemia and invasive candidiasis.