학술논문
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis
Document Type
Article
Author
Li, You; Wang, Xin; Blau, Dianna M; Caballero, Mauricio T; Feikin, Daniel R; Gill, Christopher J; Madhi, Shabir A; Omer, Saad B; Simões, Eric A F; Campbell, Harry; Pariente, Ana Bermejo; Bardach, Darmaa; Bassat, Quique; Casalegno, Jean-Sebastien; Chakhunashvili, Giorgi; Crawford, Nigel; Danilenko, Daria; Do, Lien Anh Ha; Echavarria, Marcela; Gentile, Angela; Gordon, Aubree; Heikkinen, Terho; Huang, Q Sue; Jullien, Sophie; Krishnan, Anand; Lopez, Eduardo Luis; Markić, Joško; Mira-Iglesias, Ainara; Moore, Hannah C; Moyes, Jocelyn; Mwananyanda, Lawrence; Nokes, D James; Noordeen, Faseeha; Obodai, Evangeline; Palani, Nandhini; Romero, Candice; Salimi, Vahid; Satav, Ashish; Seo, Euri; Shchomak, Zakhar; Singleton, Rosalyn; Stolyarov, Kirill; Stoszek, Sonia K; von Gottberg, Anne; Wurzel, Danielle; Yoshida, Lay-Myint; Yung, Chee Fu; Zar, Heather J; Abram, Michael; Aerssens, Jeroen; Alafaci, Annette; Balmaseda, Angel; Bandeira, Teresa; Barr, Ian; Batinović, Ena; Beutels, Philippe; Bhiman, Jinal; Blyth, Christopher C; Bont, Louis; Bressler, Sara S; Cohen, Cheryl; Cohen, Rachel; Costa, Anna-Maria; Crow, Rowena; Daley, Andrew; Dang, Duc-Anh; Demont, Clarisse; Desnoyers, Christine; Díez-Domingo, Javier; Divarathna, Maduja; du Plessis, Mignon; Edgoose, Madeleine; Ferolla, Fausto Martín; Fischer, Thea K; Gebremedhin, Amanuel; Giaquinto, Carlo; Gillet, Yves; Hernandez, Roger; Horvat, Come; Javouhey, Etienne; Karseladze, Irakli; Kubale, John; Kumar, Rakesh; Lina, Bruno; Lucion, Florencia; MacGinty, Rae; Martinon-Torres, Federico; McMinn, Alissa; Meijer, Adam; Milić, Petra; Morel, Adrian; Mulholland, Kim; Mungun, Tuya; Murunga, Nickson; Newbern, Claire; Nicol, Mark P; Odoom, John Kofi; Openshaw, Peter; Ploin, Dominique; Polack, Fernando P; Pollard, Andrew J; Prasad, Namrata; Puig-Barberà, Joan; Reiche, Janine; Reyes, Noelia; Rizkalla, Bishoy; Satao, Shilpa; Shi, Ting; Sistla, Sujatha; Snape, Matthew; Song, Yanran; Soto, Giselle; Tavakoli, Forough; Toizumi, Michiko; Tsedenbal, Naranzul; van den Berge, Maarten; Vernhes, Charlotte; von Mollendorf, Claire; Walaza, Sibongile; Walker, Gregory; Nair, Harish
Source
The Lancet; 20220101, Issue: Preprints
Subject
Language
ISSN
01406736; 1474547X
Abstract
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young children. We previously estimated that in 2015, 33·1 million episodes of RSV-associated acute lower respiratory infection occurred in children aged 0–60 months, resulting in a total of 118 200 deaths worldwide. Since then, several community surveillance studies have been done to obtain a more precise estimation of RSV associated community deaths. We aimed to update RSV-associated acute lower respiratory infection morbidity and mortality at global, regional, and national levels in children aged 0–60 months for 2019, with focus on overall mortality and narrower infant age groups that are targeted by RSV prophylactics in development.