학술논문
Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis?
Document Type
Article
Author
Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María C.; Fiol, Marcela; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica; Barboza, Andrés; Piedrabuena, Raúl; Blaya, Patricio; Steinberg, Judith; Martínez, Alejandra; Carrá, Adriana; Tavolini, Darío; López, Pablo; Knorre, Eduardo; Nofal, Pedro; Volman, Gabriel; Carnero Contentti, Edgar; Pinheiro, Amelia Alves; Leguizamon, Felisa; Silva, Emanuel; Hryb, Javier; Balbuena, María Eugenia; Zanga, Gisela; Kohler, Matías; Chertcoff, Aníbal; Lazaro, Luciana; Tizio, Santiago; Mainela, Carolina; Reich, Edgardo; Recchia, Luciano; Blanche, Jorge; Marcilla, Marcela Parada; Fracaro, María Eugenia; Sgrilli, Gustavo; Divi, Pablo; Jacobo, Miguel; Cabrera, Mariela; Pagani Cassara, Fátima; Sinay, Vladimiro; Curbelo, Celeste; Míguez, Jimena; Coppola, Mariano; Liguori, Nora Fernández; Martos, Iván; Pettinicchi, Juan Pablo; Viglione, Juan Pablo; José, Gustavo; Bestoso, Santiago; Manzi, Rubén; Vázquez, Guido; Nadur, Débora; Martínez, Carlos; Serena, Marina Alonso; Rojas, Juan I.
Source
Multiple Sclerosis and Related Disorders; 20210101, Issue: Preprints
Subject
Language
ISSN
22110348
Abstract
•Data in cohort MS studies is seldom disaggregated by sex and males are poorly considered.•Results in MS studies may be markedly biased by the female predominance of the disease.•Men present as double the frequency of PPMS than women.•Clinical and demographic data differ between men and women mostly due to the disease course than to sex.•It's crucial to include stratified analysis by sex and phenotype when designing MS studies.