학술논문
Deep RNA Sequencing Revealed Fusion Junctional Heterogeneity May Predict Crizotinib Treatment Efficacy in ALK-Rearranged NSCLC
Document Type
Article
Author
Source
Journal of Thoracic Oncology; 20210101, Issue: Preprints
Subject
Language
ISSN
15560864; 15561380
Abstract
Gene fusion variants in ALK-rearranged NSCLC may predict patient outcomes, but previous results have been inconclusive. Fusion isoforms coexisting in the same tumor may affect the efficacy of targeted therapy, but they have not been investigated.