부산대학교 도서관

ABSTRACTOn the basis of biochemical, phenotypic, and 16S rRNA analyses,Helicobacter caniswas isolated from Bengal cats with and without chronic diarrhea. Because the cats were coinfected with other potential pathogens, including Campylobacter helveticus, and because H. caniswas isolated from nondiarrheic cats, the causal role of H. canisin producing the diarrhea could not be proven. Histologically, the colons of the four affected cats were characterized by mild to moderate neutrophilic, plasmacytic, and histocytic infiltrates in the lamina propria. Rare crypt abscesses were also noted for three cats but were a more prominent feature of the colonic lesions noted for the fourth cat. This is the first observation of H. canisin cats and raises the possibility thatH. canis, like H. hepaticusand H. bilisin mice, can cause inflammation of the colon, particularly in hosts with immune dysregulation. Further studies are needed to determine the importance of H. canisas a primary enteric pathogen in cats and the role of cats in the possible zoonotic spread of H. canisto humans.