학술논문
Adiponectin Is Independently Associated With Insulin Sensitivity in Women With Polycystic Ovary Syndrome
Document Type
Article
Author
Source
Obstetrical and Gynecological Survey; April 2005, Vol. 60 Issue: 4 p237-239, 3p
Subject
Language
ISSN
00297828; 15339866
Abstract
The obesity and insulin resistance that characterize polycystic ovary syndrome (PCOS) predispose to both type 2 diabetes and atherosclerosis. Correction of metabolic abnormalities, particularly insulin resistance, reportedly can lessen hyperandrogenism and enhance fertility. Adiponectin recently was identified as an adipocytokine having insulin-sensitizing and possibly antiatherosclerotic effects. This study sought to identify determinants of circulating adiponectin and its potential for reversing insulin resistance in 62 consecutive women with PCOS who were compared with 35 healthy control women.