학술논문
Citron kinase controls abscission through RhoA and anillin
Document Type
Article
Author
Source
Molecular Biology of the Cell; October 2011, Vol. 22 Issue: 20 p3768-3778, 11p
Subject
Language
ISSN
10591524; 19394586
Abstract
In this report, we confirm that the RhoA-binding protein citron kinase (CIT-K) is required for midbody abscission in late cytokinesis, while it has little or no role in early cytokinesis. Moreover, we show that CIT-K, despite being commonly considered a RhoA effector, promotes midbody stability through RhoA and anillin during late cytokinesis.