학술논문
Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology
Document Type
Article
Author
Little, Ross A.; Jamin, Yann; Boult, Jessica K. R.; Naish, Josephine H.; Watson, Yvonne; Cheung, Susan; Holliday, Katherine F.; Lu, Huiqi; McHugh, Damien J.; Irlam, Joely; West, Catharine M. L.; Betts, Guy N.; Ashton, Garry; Reynolds, Andrew R.; Maddineni, Satish; Clarke, Noel W.; Parker, Geoff J. M.; Waterton, John C.; Robinson, Simon P.; O’Connor, James P. B.
Source
Radiology; September 2018, Vol. 288 Issue: 3 p739-747, 9p
Subject
Language
ISSN
00338419; 15271315
Abstract
Intrinsic susceptibility imaging and immunohistochemistry analysis were used to validate a combined endpoint of oxygen enhancement plus MR-derived perfusion as a biomarker of tumor hypoxia in mouse and patient studies.