학술논문
Direct Whole-Genome Sequencing of Sputum Accurately Identifies Drug-Resistant Mycobacterium tuberculosisFaster than MGIT Culture Sequencing
Document Type
Article
Author
Doyle, Ronan M.; Burgess, Carrie; Williams, Rachel; Gorton, Rebecca; Booth, Helen; Brown, James; Bryant, Josephine M.; Chan, Jackie; Creer, Dean; Holdstock, Jolyon; Kunst, Heinke; Lozewicz, Stefan; Platt, Gareth; Romero, Erika Yara; Speight, Graham; Tiberi, Simon; Abubakar, Ibrahim; Lipman, Marc; McHugh, Timothy D.; Breuer, Judith
Source
Journal of Clinical Microbiology; May 2018, Vol. 56 Issue: 8
Subject
Language
ISSN
00951137; 1098660X
Abstract
The current methods available to diagnose antimicrobial-resistant Mycobacterium tuberculosisinfections require a positive culture or only test a limited number of resistance-associated mutations. A rapid accurate identification of antimicrobial resistance enables the prompt initiation of effective treatment.