학술논문
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Document Type
Article
Author
Ndila, Carolyne M; Uyoga, Sophie; Macharia, Alexander W; Nyutu, Gideon; Peshu, Norbert; Ojal, John; Shebe, Mohammed; Awuondo, Kennedy O; Mturi, Neema; Tsofa, Benjamin; Sepúlveda, Nuno; Clark, Taane G; Band, Gavin; Clarke, Geraldine; Rowlands, Kate; Hubbart, Christina; Jeffreys, Anna; Kariuki, Silvia; Marsh, Kevin; Mackinnon, Margaret; Maitland, Kathryn; Kwiatkowski, Dominic P; Rockett, Kirk A; Williams, Thomas N; Abathina, Amadou; Abubakar, Ismaela; Achidi, Eric; Agbenyega, Tsiri; Aiyegbo, Mohammed; Akoto, Alex; Allen, Angela; Allen, Stephen; Amenga-Etego, Lucas; Amodu, Folakemi; Amodu, Olukemi; Anchang-Kimbi, Judith; Ansah, Nana; Ansah, Patrick; Ansong, Daniel; Antwi, Sampson; Anyorigiya, Thomas; Apinjoh, Tobias; Asafo-Agyei, Emmanuel; Asoala, Victor; Atuguba, Frank; Auburn, Sarah; Bah, Abdou; Bamba, Kariatou; Bancone, Germana; Band, Gavin; Barnwell, David; Barry, Abdoulaye; Bauni, Evasius; Besingi, Richard; Bojang, Kalifa; Bougouma, Edith; Bull, Susan; Busby, George; Camara, Abdoulie; Camara, Landing; Campino, Susana; Carter, Richard; Carucci, Dan; Casals-Pascual, Climent; Ceesay, Ndey; Ceesay, Pa; Chau, Tran; Chuong, Ly; Clark, Taane; Clarke, Geraldine; Cole-Ceesay, Ramou; Conway, David; Cook, Katharine; Cook, Olivia; Cornelius, Victoria; Corran, Patrick; Correa, Simon; Cox, Sharon; Craik, Rachel; Danso, Bakary; Davis, Timothy; Day, Nicholas; Deloukas, Panos; Dembele, Awa; deVries, Jantina; Dewasurendra, Rajika; Diakite, Mahamadou; Diarra, Elizabeth; Dibba, Yaya; Diss, Andrea; Djimdé, Abdoulaye; Dolo, Amagana; Doumbo, Ogobara; Doyle, Alan; Drakeley, Chris; Drury, Eleanor; Duffy, Patrick; Dunstan, Sarah; Ebonyi, Augustine; Elhassan, Ahmed; Elhassan, Ibrahim; Elzein, Abier; Enimil, Anthony; Esangbedo, Pamela; Evans, Jennifer; Evans, Julie; Farrar, Jeremy; Fernando, Deepika; Fitzpatrick, Kathryn; Fullah, Janet; Garcia, Jacob; Ghansah, Anita; Gottleib, Michael; Green, Angie; Hart, Lee; Hennsman, Meike; Hien, Tran; Hieu, Nguyen; Hilton, Eliza; Hodgson, Abraham; Horstmann, Rolf; Hubbart, Christina; Hughes, Catherine; Hussein, Ayman; Hutton, Robert; Ibrahim, Muntaser; Ishengoma, Deus; Jaiteh, Jula; Jallow, Mariatou; Jallow, Muminatou; Jammeh, Kebba; Jasseh, Momodou; Jeffreys, Anna; Jobarteh, Amie; Johnson, Kimberly; Joseph, Sarah; Jyothi, Dushyanth; Kachala, David; Kamuya, Dorcas; Kanyi, Haddy; Karunajeewa, Harin; Karunaweera, Nadira; Keita, Momodou; Kerasidou, Angeliki; Khan, Aja; Kivinen, Katja; Kokwaro, Gilbert; Konate, Amadou; Konate, Salimata; Koram, Kwadwo; Kwiatkowski, Dominic; Laman, Moses; Le, Si; Leffler, Ellen; Lemnge, Martha; Lin, Enmoore; Ly, Alioune; Macharia, Alexander; MacInnis, Bronwyn; Mai, Nguyen; Makani, Julie; Malangone, Cinzia; Mangano, Valentina; Manjurano, Alphaxard; Manneh, Lamin; Manning, Laurens; Manske, Magnus; Marsh, Kevin; Marsh, Vicki; Maslen, Gareth; Maxwell, Caroline; Mbunwe, Eric; McCreight, Marilyn; Mead, Daniel; Mendy, Alieu; Mendy, Anthony; Mensah, Nathan; Michon, Pascal; Miles, Alistair; Miotto, Olivo; Modiano, David; Mohamed, Hiba; Molloy, Sile; Molyneux, Malcolm; Molyneux, Sassy; Moore, Mike; Moyes, Catherine; Mtei, Frank; Mtove, George; Mueller, Ivo; Mugri, Regina; Munthali, Annie; Mutabingwa, Theonest; Nadjm, Behzad; Ndi, Andre; Ndila, Carolyne; Newton, Charles; Niangaly, Amadou; Njie, Haddy; Njie, Jalimory; Njie, Madi; Njie, Malick; Njie, Sophie; Njiragoma, Labes; Nkrumah, Francis; Ntunthama, Neema; Nyika, Aceme; Nyirongo, Vysaul; O'Brien, John; Obu, Herbert; Oduro, Abraham; Ofori, Alex; Olaniyan, Subulade; Olaosebikan, Rasaq; Oluoch, Tom; Omotade, Olayemi; Oni, Olajumoke; Onykwelu, Emmanuel; Opi, Daniel; Orimadegun, Adebola; O'Riordan, Sean; Ouedraogo, Issa; Oyola, Samuel; Parker, Michael; Pearson, Richard; Pensulo, Paul; Peshu, Norbert; Phiri, Ajib; Phu, Nguyen; Pinder, Margaret; Pirinen, Matti; Plowe, Chris; Potter, Claire; Poudiougou, Belco; Puijalon, Odile; Quyen, Nguyen; Ragoussis, Ioannis; Ragoussis, Jiannis; Rasheed, Oba; Reeder, John; Reyburn, Hugh; Riley, Eleanor; Risley, Paul; Rockett, Kirk; Rodford, Joanne; Rogers, Jane; Rogers, William; Rowlands, Kate; Ruano-Rubio, Valentín; Sabally-Ceesay, Kumba; Sadiq, Abubacar; Saidy-Khan, Momodou; Saine, Horeja; Sakuntabhai, Anavaj; Sall, Abdourahmane; Sambian, David; Sambou, Idrissa; SanJoaquin, Miguel; Sepúlveda, Nuno; Shah, Shivang; Shelton, Jennifer; Siba, Peter; Silva, Nilupa; Simmons, Cameron; Simpore, Jaques; Singhasivanon, Pratap; Sinh, Dinh; Sirima, Sodiomon; Sirugo, Giorgio; Sisay-Joof, Fatoumatta; Sissoko, Sibiry; Small, Kerrin; Somaskantharajah, Elilan; Spencer, Chris; Stalker, Jim; Stevens, Marryat; Suriyaphol, Prapat; Sylverken, Justice; Taal, Bintou; Tall, Adama; Taylor, Terrie; Teo, Yik; Thai, Cao; Thera, Mahamadou; Titanji, Vincent; Toure, Ousmane; Troye-Blomberg, Marita; Usen, Stanley; Uyoga, Sophie; Vanderwal, Aaron; Wangai, Hannah; Watson, Renee; Williams, Thomas; Wilson, Michael; Wrigley, Rebecca; Yafi, Clarisse; Yamoah, Lawrence
Source
The Lancet Haematology; August 2018, Vol. 5 Issue: 8 pe333-e345, 13p
Subject
Language
ISSN
23523026
Abstract
Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparummalaria and its specific phenotypes, including cerebral malaria, severe malaria anaemia, and respiratory distress.